Which Should You Buy: Generic Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
Generic orlistat 120mg and branded Xenical 120mg are clinically equivalent medications containing the same active ingredient at identical doses. Both work by blocking approximately one third of dietary fat absorption and require the same prescription-only clinical assessment. The primary difference lies in cost - generic orlistat offers significant savings without compromising effectiveness.
Best Time to Take Both Orlistat and Xenical
Whether you choose generic orlistat or Xenical, the dosing schedule remains identical. Take one 120mg capsule three times daily with each main meal containing fat. The optimal timing is immediately before, during, or up to one hour after eating. If you miss a meal or eat a fat-free meal, skip that dose. This timing ensures the medication works when dietary fat reaches your digestive system.
Price Comparison: Your Savings with Generic Orlistat
Generic orlistat delivers substantial cost savings compared to branded Xenical. For a 4-week supply (84 capsules), generic orlistat costs £29.69 with code EDM10, while Xenical costs £38.69 - saving you £9 monthly. Over 12 weeks, you save £30 choosing generic orlistat at £86.39 versus Xenical at £116.09. Both options include the prescription following clinical assessment by UK-licensed prescribers.
Clinical Effectiveness: No Difference
Both medications block approximately one third of dietary fat absorption through the same mechanism. Generic orlistat and Xenical produce identical clinical outcomes when used alongside a reduced-calorie, lower-fat diet and regular physical activity. Side effects, contraindications, and monitoring requirements are identical between both options.
Alternative Option: Alli 60mg
For those preferring lower-strength treatment, Alli 60mg offers half the dose of prescription orlistat. Available in 4-week supplies for £26.09 with EDM10, Alli may cause fewer gastrointestinal side effects due to the reduced strength, though clinical effectiveness is correspondingly lower.
Your Online Prescription Process
Both orlistat and Xenical require prescription following online clinical assessment. Complete our medical questionnaire covering weight history, current medications, and health conditions. UK-licensed prescribers review your information and issue prescriptions where clinically appropriate. Orders are dispensed by our GPhC-registered Leicester pharmacy with next day delivery across the UK.
Maximising Your Treatment Success
Regardless of whether you choose generic orlistat or Xenical, success depends on consistent timing and dietary compliance. Keep meals below 15g fat content to minimise side effects. Take a multivitamin at bedtime to replace fat-soluble vitamins. Both medications work best as part of structured weight management including regular exercise and behavioural support.


