Choose Generic Orlistat or Branded Xenical Today
Orlistat vs Xenical: The Facts
Both Orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. They work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. The clinical effect is the same - the main difference is cost. Generic orlistat offers significant savings compared to branded Xenical.
Price Comparison: Save with Generic
Generic orlistat 120mg costs £16.89 for a 2-week supply (£15.20 with EDM10), while branded Xenical costs £21.50 (£19.35 with EDM10). For a 4-week supply, choose orlistat at £32.99 (£29.69 with EDM10) or Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, generic orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10) - a saving of over £29.
Managing Constipation on Orlistat
Constipation can occur with orlistat treatment. Both generic orlistat and Xenical may cause this side effect equally. Keeping dietary fat intake low (approximately 15g per meal) helps minimise gastrointestinal side effects. Drinking plenty of water and including fibre-rich foods in your reduced-calorie diet may help. If constipation persists, consult your healthcare professional.
Consider Alli 60mg as Alternative
Alli 60mg contains half the dose of prescription orlistat and may cause milder side effects including less constipation. Available without prescription, Alli costs £28.99 for a 4-week supply (£26.09 with EDM10). While less potent than 120mg versions, it may suit those experiencing troublesome side effects with higher-dose orlistat.
Which Should You Choose?
Choose generic orlistat 120mg for the best value - clinically identical to Xenical but significantly cheaper. Select branded Xenical if you prefer the original Roche product. Both require prescription following online clinical assessment by a UK-licensed prescriber. Treatment is dispensed by our GPhC-registered pharmacy with discreet next-day delivery across the UK.
Order Today with 10% Discount
Save 10% on every orlistat or Xenical order with code EDM10 - available to new and returning customers. Complete our online clinical assessment to start your weight management journey. Our UK-licensed prescribers will review your suitability for treatment and prescribe where clinically appropriate.


