Which Alli Weight Loss Drug Should You Choose?
Orlistat 120mg vs Xenical 120mg: The Key Differences
Generic orlistat 120mg and branded Xenical 120mg are clinically equivalent medications containing the same active ingredient at identical doses. Both work by inhibiting lipase enzymes in the gut to block approximately one third of dietary fat absorption. The primary difference lies in cost and manufacturer - generic orlistat offers substantial savings while delivering the same clinical effect as branded Xenical.
Cost Comparison: Orlistat vs Xenical Pricing
Generic orlistat provides excellent value for money. A 4-week supply (84 capsules) costs £32.99, reduced to £29.69 with code EDM10. The same quantity of branded Xenical costs £42.99, or £38.69 with EDM10 - representing a saving of £9 per month when choosing generic orlistat. For longer treatments, a 12-week supply of orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical's £128.99 (£116.09 with EDM10) - a total saving of £29.70.
Alli 60mg: Lower Strength Alternative
Alli contains half the dose of prescription-strength orlistat at 60mg per capsule. This lower-strength option may suit those preferring a gentler starting point, though it blocks a smaller proportion of dietary fat compared to 120mg formulations. Alli 60mg costs £28.99 for a 4-week supply (42 capsules), reduced to £26.09 with EDM10. All strengths require the same dosing schedule - one capsule with each main meal containing fat, up to three times daily.
Who May Be Suitable for Orlistat Treatment
Following online clinical assessment, orlistat may be prescribed for adults with a BMI of 30 kg/m² or above, or those with a BMI of 28 kg/m² or above with weight-related health conditions such as type 2 diabetes or high blood pressure. Treatment suitability is determined by qualified UK-licensed prescribers who review individual health circumstances, medical history and current medications during the online consultation process.
How All Three Options Work
Whether you choose generic orlistat, branded Xenical or lower-strength Alli, the mechanism remains the same. Each medication works locally in the digestive system by blocking lipase enzymes responsible for breaking down dietary fat. Approximately one third of consumed fat cannot be absorbed and passes naturally through the body. This reduction in absorbed calories can support weight management when combined with a reduced-calorie, lower-fat diet and regular physical activity.
Managing Side Effects Across All Strengths
All orlistat-containing medications may cause gastrointestinal side effects, particularly when consuming high-fat meals. Common effects include oily stools, increased bowel frequency and abdominal discomfort. These effects can be minimised by keeping daily fat intake to approximately 15g per meal, spread evenly across three main meals. Side effects are often a sign the medication is working by preventing fat absorption.
Order Your Chosen Treatment Today
Complete our online consultation to begin your weight management journey with your preferred option. Our UK-licensed prescribers will assess your suitability for treatment, and if appropriate, your medication will be dispensed by our GPhC-registered pharmacy in Leicester. Next day delivery is available across the UK with discreet, secure packaging. Use code EDM10 for 10% off your order, whether choosing cost-effective generic orlistat, branded Xenical, or lower-strength Alli.


