Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: The Clinical Facts
Both orlistat 120mg capsules and Xenical 120mg capsules contain the exact same active ingredient at identical doses. Clinically, they work in precisely the same way — blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in your digestive system. Your body cannot distinguish between generic orlistat and branded Xenical once absorbed, making them therapeutically equivalent options for weight management.
Cost Comparison: Your 30-Day Investment
For a 4-week supply (84 capsules), generic orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10). Over 30 days, you'll save approximately £9 choosing generic orlistat — that's over £100 annual savings for identical clinical results. For longer treatment periods, the savings are even more substantial: a 12-week orlistat supply costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10).
What to Expect in Your First 30 Days
Both orlistat and Xenical may help support weight management when used alongside a reduced-calorie, lower-fat diet containing no more than 30% calories from fat. Individual responses vary significantly, but the medication works immediately with each fat-containing meal. Most patients experience gastrointestinal side effects initially — these typically reduce as you adapt to lower-fat eating patterns. Keep meals to approximately 15g fat each to minimise side effects whilst maximising effectiveness.
Alli 60mg: The Lower-Strength Alternative
If you prefer starting with a lower dose, Alli 60mg capsules offer half the strength of prescription orlistat. At £28.99 for a 4-week supply (£26.09 with EDM10), Alli provides a gentler introduction to orlistat treatment, though with correspondingly reduced fat-blocking capacity. This option doesn't require a prescription and may suit those wanting to trial orlistat's effects before progressing to full-strength treatment.
Your Online Prescription Process
Both orlistat 120mg and Xenical 120mg require prescription following clinical assessment. Our UK-licensed prescribers review your online health questionnaire, considering your BMI, medical history, and weight management goals. Suitable patients typically have a BMI of 30+ or 28+ with weight-related health conditions. Once prescribed, your chosen medication is dispensed by our GPhC-registered pharmacy and delivered discreetly to your address with next-day delivery available.
Making Your Decision
Choose generic orlistat 120mg for maximum value whilst maintaining full clinical effectiveness. Choose Xenical 120mg if you prefer branded medication from Roche. Both options block the same amount of dietary fat and support identical weight management outcomes. Your decision ultimately comes down to budget preferences — the clinical benefits remain constant regardless of your choice.


