Which Should You Choose: Generic or Branded?
Orlistat 120mg vs Xenical 120mg: Clinical Comparison
Both orlistat 120mg and Xenical 120mg contain the same active ingredient at identical doses. Clinically, they work in exactly the same way - blocking approximately one third of dietary fat absorption through lipase enzyme inhibition in the gut. The choice between generic orlistat and branded Xenical often comes down to personal preference and budget considerations.
Cost Comparison: Why Choose Generic Orlistat?
Generic orlistat offers substantial savings over Xenical. A 4-week supply of orlistat costs £29.69 with code EDM10, compared to £38.69 for Xenical - saving £9 per month. For a 12-week supply, you'll save £29.70 by choosing generic orlistat (£86.39) over Xenical (£116.09). Over a typical weight management programme, these savings can be significant whilst maintaining identical clinical benefits.
Prescription Process for Both Options
Both orlistat 120mg and Xenical require a prescription following clinical assessment. Our UK-licensed prescribers review your medical history, current medications, and weight management goals to determine suitability. The online consultation takes minutes to complete, and approved prescriptions are dispensed by our GPhC-registered pharmacy in Leicester.
Pack Sizes and Treatment Duration
We stock comprehensive ranges of both products. Orlistat 120mg is available in 42 capsules (2 weeks, £15.20 with EDM10), 84 capsules (4 weeks, £29.69), 168 capsules (8 weeks, £57.59), and 252 capsules (12 weeks, £86.39). Xenical follows the same pattern at higher prices. Most patients start with a 4-week supply to assess tolerance before progressing to longer-term supplies.
Alli 60mg: The Lower-Strength Alternative
For those preferring a gentler starting point, Alli 60mg contains half the dose of prescription orlistat. At 60mg, it typically produces milder gastrointestinal effects whilst still supporting weight management alongside a reduced-calorie, lower-fat diet. Alli costs £26.09 for 4 weeks with code EDM10.
How All Three Products Work
Whether you choose orlistat, Xenical, or Alli, the mechanism remains the same. The medication works locally in your digestive system, inhibiting lipase enzymes that break down dietary fat. This means approximately one third of the fat you consume cannot be absorbed and passes through your body naturally. The effect is directly related to meal fat content - lower fat meals result in fewer side effects.
Making Your Decision
Most patients choose generic orlistat for the cost savings without compromising clinical effectiveness. Some prefer branded Xenical for familiarity or personal preference. Either way, you'll receive the same high-quality service from our pharmacy, including discreet packaging and next day delivery. Complete your online consultation to discuss which option best suits your weight management journey.


