Compare Orlistat vs Saxenda: Expert Pharmacy Guidance
Orlistat vs Saxenda: How They Work Differently
Orlistat and Saxenda work through completely different mechanisms for weight management. Orlistat 120mg works locally in your digestive system, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. Saxenda (liraglutide) is an injectable GLP-1 receptor agonist that works on appetite centres in the brain, helping you feel fuller for longer and reducing food cravings. Both treatments require prescription following clinical assessment by our UK-licensed prescribers.
Treatment Format and Administration
Orlistat is taken as oral capsules - one 120mg capsule with each main meal containing fat, up to three times daily. Our pharmacy stocks 2-week supplies (42 capsules) from £16.89, with 12-week supplies (252 capsules) at £95.99. Saxenda requires daily subcutaneous injections using a pre-filled pen, starting with dose escalation over several weeks. Many patients find orlistat capsules more convenient than daily injections, though individual preferences vary significantly.
Suitability and Assessment Process
Both medications are suitable for adults with BMI ≥30 kg/m² or BMI ≥28 kg/m² with weight-related health conditions. Our online clinical assessment determines individual suitability based on your medical history, current medications, and weight management goals. Orlistat may be preferred for patients who prefer oral medication and can follow a reduced-calorie, lower-fat diet. Saxenda may be considered for patients requiring appetite suppression support. Complete our confidential questionnaire for personalised prescriber review.
Side Effect Profiles
Orlistat's side effects are primarily gastrointestinal and directly related to dietary fat intake - including oily stools, increased bowel movement frequency, and abdominal discomfort. These can be minimised by keeping meals low in fat (approximately 15g per meal). Saxenda's side effects commonly include nausea, diarrhoea, constipation, and potential injection site reactions. Both medications require healthcare professional monitoring, and our prescribers provide ongoing support throughout treatment.
Cost Comparison and Value
Orlistat offers significant cost advantages compared to Saxenda. Our generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), while branded Xenical costs £42.99 for 4 weeks (£38.69 with EDM10). Saxenda typically costs significantly more per month. All prices include prescription fees and clinical assessment by our UK-licensed prescribers. Use discount code EDM10 for 10% off every order - available for new and returning customers.
Why Choose EverydayMeds
As a GPhC-registered online pharmacy based in Leicester, we provide MHRA-regulated access to both orlistat and Saxenda through qualified UK prescribers. Our streamlined process eliminates GP waiting times while maintaining the same clinical standards. All medication is sourced through licensed UK pharmaceutical supply chains and delivered discreetly with next-day tracking. Start your clinical assessment today to determine which treatment may be most appropriate for your individual circumstances.
