Choose Your Prescription Weight Loss Treatment
Key Differences: Orlistat 120mg vs Alli 60mg
The primary difference between orlistat and Alli lies in their strength and prescription requirements. Orlistat 120mg is prescription-only and blocks approximately one third of dietary fat absorption, making it the most clinically effective option. Available as generic orlistat (from £29.69 for 4 weeks with EDM10) or branded Xenical (£38.69 for 4 weeks with EDM10), both contain identical active ingredients.
Alli 60mg offers half the strength at £26.09 for 4 weeks with EDM10. This lower-strength option may be suitable for those preferring a gentler introduction to fat-blocking treatment. All options require commitment to a reduced-calorie, lower-fat diet for optimal results.
Clinical Effectiveness and Mechanism
Both orlistat 120mg and Alli work by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your body. Prescription-strength orlistat 120mg provides maximum clinical effectiveness, whilst Alli 60mg offers a lower-strength alternative.
These treatments work best when combined with meals containing no more than 15g fat per serving. Higher fat intake increases the likelihood of gastrointestinal side effects, which are the body's natural response to unabsorbed fat.
Prescription Process and Clinical Assessment
Orlistat 120mg requires clinical assessment by our UK-licensed prescribers, who review your medical history, current medications, and BMI to determine suitability. Treatment may be appropriate for adults with BMI 30+ or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure.
Our online consultation replaces the need for a GP appointment, with prescriptions issued where clinically appropriate. Complete your assessment today - prescription approval typically takes 24 hours, followed by discreet next day delivery from our GPhC-registered Leicester pharmacy.
Pricing and Value Comparison
Generic orlistat 120mg offers exceptional value at £29.69 for 4 weeks (84 capsules) with code EDM10, compared to £38.69 for branded Xenical. For longer treatment periods, our 12-week supply costs £86.39 with EDM10 - significant savings versus monthly purchases.
Alli 60mg costs £26.09 for 4 weeks with EDM10. However, the lower strength means you're paying similar amounts for half the clinical potency. Most patients find generic orlistat 120mg provides better value for comprehensive weight management support.
Managing Treatment and Side Effects
Both treatments may cause gastrointestinal side effects including oily stools, increased bowel frequency, and abdominal discomfort. These effects are significantly reduced by keeping dietary fat low - aim for maximum 15g fat per meal spread across three daily meals.
Taking a multivitamin supplement at bedtime is recommended, as orlistat may reduce absorption of fat-soluble vitamins A, D, E, and K. Most side effects diminish as your diet adapts to lower fat intake, typically within the first few weeks of treatment.
Order Your Weight Loss Treatment Today
Ready to start your prescription weight loss journey? Complete our online clinical assessment to determine whether orlistat 120mg or Alli 60mg is right for you. Use code EDM10 for 10% off every order, with next day delivery available across the UK. Our customer service team provides ongoing support throughout your treatment.
