How Orlistat Works for Weight Management
How Does Orlistat Work on Dietary Fat?
Orlistat works by blocking lipase enzymes in your digestive system, preventing approximately one third of the fat you eat from being absorbed. This unabsorbed fat passes naturally through your body. Orlistat doesn't work on existing stored body fat - instead, it reduces the amount of new fat your body can absorb from meals. This may help create a calorie deficit when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Prescription Weight Loss Options at EverydayMeds
We offer three clinically proven options for prescription weight loss treatment. Orlistat 120mg (generic) provides the most cost-effective option at £32.99 for 4 weeks (£29.69 with EDM10). Xenical 120mg contains the same active ingredient as generic orlistat but costs £42.99 for 4 weeks (£38.69 with EDM10). Alli 60mg offers a lower-strength alternative at £54.99 for 8 weeks (£49.49 with EDM10).
Clinical Assessment and Prescription Process
All orlistat 120mg prescriptions require clinical assessment by a UK-licensed prescriber. Complete our online health questionnaire covering your medical history, current medications and weight management goals. Our prescriber will review your information and issue a prescription where clinically appropriate. The entire process typically takes 24 hours from assessment to delivery.
Expected Results and Realistic Expectations
Orlistat may help support weight management when used alongside dietary and lifestyle changes. The medication works best when you follow a reduced-calorie diet with no more than 30% of calories from fat (approximately 15g fat per meal). Higher fat meals increase the likelihood of gastrointestinal side effects. Individual responses vary, and long-term success depends on maintaining healthy eating habits and regular physical activity.
Managing Side Effects During Treatment
Most orlistat side effects are gastrointestinal and directly related to dietary fat intake. Common effects include oily stools, increased bowel frequency and urgent need for the toilet. These effects can be minimised significantly by keeping meals low in fat. If you experience severe abdominal pain, seek medical advice immediately.
Order Your Prescription Weight Loss Treatment
Start your weight management journey with prescription orlistat from EverydayMeds. Use code EDM10 for 10% off your order, with prices starting from £15.20 for 2 weeks of treatment. Our GPhC-registered pharmacy in Leicester dispatches orders same day with tracked next day delivery across the UK.


