Understanding Orlistat's Mechanism - Order Now
How Orlistat Fat Blocking Works
Orlistat works through a targeted mechanism in your digestive system. It inhibits lipase enzymes responsible for breaking down dietary fat, preventing approximately one third of fat consumed from being absorbed into your body. This unabsorbed fat passes naturally through your digestive system, reducing overall calorie intake from dietary sources. The mechanism acts locally in your gut rather than being absorbed into your bloodstream, making it different from appetite suppressants that work on your brain.
Why This Mechanism Supports Weight Loss
By blocking approximately one third of dietary fat absorption, orlistat can support your weight management programme alongside a reduced-calorie, lower-fat diet. Fat contains 9 calories per gram - more than double that of carbohydrates or protein. When orlistat prevents fat absorption, those calories cannot contribute to weight gain. This proven mechanism has helped support weight loss in clinical studies when combined with dietary changes.
Orlistat Products Available at EverydayMeds
Our prescription orlistat 120mg starts from £16.89 for 42 capsules (£15.20 with EDM10), offering the most cost-effective option. Branded Xenical 120mg provides the same mechanism at £21.50 for 42 capsules (£19.35 with EDM10). Both work identically - blocking approximately one third of dietary fat absorption. Alli 60mg at £28.99 for 42 capsules offers half the prescription dose for those preferring a lower-strength option.
Maximising Orlistat's Fat-Blocking Effect
Understanding orlistat's mechanism helps you use it effectively. Take one capsule with each main meal containing fat, up to three times daily. Keep meals low in fat (approximately 15g per meal) to maximise benefits whilst minimising gastrointestinal side effects. The medication works best when dietary fat is spread evenly across three meals rather than consumed in large amounts at once.
Order Your Orlistat Today
Now you understand how orlistat blocks approximately one third of dietary fat absorption, you can make an informed purchase decision. Complete our online clinical assessment to have your suitability reviewed by a UK-licensed prescriber. Following approval, your orlistat will be dispensed by our Leicester GPhC-registered pharmacy and delivered discreetly next day. Use code EDM10 for 10% off your order.


