Orlistat vs Xenical: Price Comparison & Buying Guide
Generic Orlistat vs Xenical: What's the Difference?
Generic orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Both work by blocking approximately one third of dietary fat absorption when taken alongside a reduced-calorie, lower-fat diet. The key difference lies in price and manufacturer - generic orlistat offers clinically equivalent treatment at significantly lower cost.
Orlistat Price UK: Cost Comparison
Generic orlistat 120mg: 4-week supply (84 capsules) costs £32.99, reduced to £29.69 with EDM10. Xenical 120mg: 4-week supply costs £42.99, reduced to £38.69 with EDM10. This represents monthly savings of approximately £9 when choosing generic orlistat over branded Xenical.
Longer-term supplies offer better value: 12-week generic orlistat costs £86.39 with EDM10 versus Xenical at £116.09 - saving nearly £30 over three months.
Alli 60mg: Lower-Strength Alternative
Alli 60mg provides half the dose of prescription-strength orlistat. At £26.09 for 4-week supply (with EDM10), it offers an option for those preferring lower-strength treatment. However, clinical effect is correspondingly reduced compared to 120mg prescription products.
Which Should You Choose?
Generic orlistat delivers identical clinical results to Xenical whilst offering substantial savings. Both require prescription following clinical assessment by qualified UK-licensed prescribers. Some patients prefer branded Xenical, whilst others choose generic orlistat for value. Your prescriber can help determine which option suits your treatment plan and budget.
How to Order
Complete our online clinical assessment questionnaire. A UK-licensed prescriber reviews your information and issues prescription where clinically appropriate. Orders are dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly with next-day delivery available. Use code EDM10 for 10% off every order.
Treatment Requirements
Both orlistat and Xenical must be used alongside reduced-calorie, lower-fat diet and regular physical activity. Treatment suitability depends on individual clinical assessment - typically suitable for adults with BMI 30+ or BMI 28+ with weight-related health conditions. Take one 120mg capsule three times daily with main meals containing fat.


