Why Understanding the Mechanism Matters for Your Choice
The Science Behind Orlistat's Fat-Blocking Action
Orlistat works by inhibiting lipase enzymes in your digestive system that normally break down dietary fat. When these enzymes are blocked, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your system, reducing the calories your body takes in from dietary fat. The mechanism is the same whether you choose generic orlistat 120mg (£29.69 for 4 weeks with EDM10) or branded Xenical 120mg (£38.69 for 4 weeks with EDM10).
Why Both Products Work Identically
Orlistat and Xenical contain exactly the same active ingredient at the same 120mg dose. The fat-blocking mechanism is identical - both inhibit approximately one third of dietary fat absorption. The key difference is cost: generic orlistat offers the same clinical effect as Xenical but saves you around £9 monthly. Whether you prefer the branded option or value-focused generic, you get the same proven fat-blocking action that works locally in your gut.
What This Means for Your Weight Management
Understanding that orlistat blocks approximately one third of dietary fat helps explain why it must be combined with a reduced-calorie, lower-fat diet. The medication doesn't block all fat - it reduces absorption while encouraging healthier eating habits. This mechanism makes orlistat particularly effective when meals contain moderate amounts of fat (around 15g per meal). Higher fat intake increases both the fat-blocking effect and potential gastrointestinal side effects.
Comparing Your Options at EverydayMeds
Generic orlistat 120mg provides excellent value: 8-week supply for £57.59 with EDM10 versus Xenical's £78.29 for the same period. For those preferring lower-dose options, Alli 60mg (£49.49 for 8 weeks with EDM10) contains half the orlistat dose, blocking a smaller proportion of dietary fat. All three options require clinical assessment by our UK-licensed prescribers, with next day delivery available across the UK from our GPhC-registered pharmacy in Leicester.
Ready to Start Your Treatment?
Now you understand how orlistat's fat-blocking mechanism works, you can make an informed choice between generic orlistat, branded Xenical, or lower-dose Alli. Our online clinical assessment takes just minutes, with prescriber review and pharmacy dispensing handled efficiently. Use code EDM10 for 10% off your order - the discount applies to new and returning customers alike.


