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How Orlistat Works: The Science Behind Fat Blocking
Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks these enzymes, approximately one third of the fat you eat cannot be digested or absorbed. This unabsorbed fat passes naturally through your digestive system and is eliminated from your body.
Unlike appetite suppressants that work in your brain, orlistat acts locally in your gut and is not significantly absorbed into your bloodstream. This targeted mechanism makes it a different approach to weight management compared to other treatments.
Why Understanding the Mechanism Matters for Your Purchase Decision
Knowing that orlistat blocks approximately one third of dietary fat absorption helps you understand what to expect from treatment. This isn't a complete fat blocker - the remaining two thirds of fat is still absorbed normally. The medication works best when you keep your fat intake low (around 15g per meal) to minimise side effects whilst supporting weight loss.
Generic orlistat 120mg offers this proven mechanism from £32.99 for 4 weeks (£29.69 with EDM10), whilst branded Xenical provides the identical effect at £42.99 for 4 weeks (£38.69 with EDM10). Both contain the same active ingredient at the same 120mg dose.
What Happens When You Take Orlistat
When you take one 120mg capsule with each main meal containing fat, orlistat gets to work immediately in your digestive system. The blocked fat that cannot be absorbed may cause gastrointestinal effects like oily stools or urgent bowel movements - these are actually signs the medication is working as intended.
You'll take three capsules daily - one with breakfast, lunch, and dinner. If you miss a meal or eat something fat-free, you can skip that dose. Most people see the fat-blocking effects within 24-48 hours of starting treatment.
Your Options: Generic vs Branded, 120mg vs 60mg
At EverydayMeds, you can choose from three clinically-proven options following prescriber assessment. Generic orlistat 120mg provides maximum fat-blocking at the lowest cost - perfect if you want proven results without paying for branding. A 12-week supply costs £95.99 (£86.39 with EDM10).
Xenical 120mg contains exactly the same orlistat but as the original branded version from Roche. Some patients prefer the brand recognition, though the clinical effect is identical to generic. A 12-week supply costs £128.99 (£116.09 with EDM10).
Alli 60mg offers half the prescription dose for those preferring to start with lower-strength treatment. At 60mg, it blocks a smaller proportion of dietary fat with typically milder side effects.
Getting Your Prescription: Fast, Regulated, Legitimate
EverydayMeds makes accessing orlistat straightforward through our online clinical assessment. A UK-licensed prescriber reviews your medical history, current medications, and weight management goals. If treatment is appropriate for your circumstances, your prescription is issued and dispensed by our GPhC-registered pharmacy in Leicester.
Your orlistat is dispatched with next day delivery across the UK in discreet packaging. Use code EDM10 for 10% off every order - this applies to new and returning customers. The prescription consultation is included in the price, so you avoid separate GP appointment fees.
