The Science Behind Orlistat's Fat Blocking Action
How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed. When orlistat blocks them, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your system, reducing your calorie intake from dietary fat.
Why This Mechanism Works for Weight Loss
Fat contains 9 calories per gram - more than twice that of carbohydrates or protein. By blocking approximately one third of dietary fat absorption, orlistat can significantly reduce your calorie intake when used alongside a reduced-calorie, lower-fat diet. This proven mechanism has made orlistat the UK's most prescribed weight loss medication for adults with a BMI of 28-30 or above.
Orlistat vs Xenical - Same Fat Blocking Power
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and block the same proportion of dietary fat. The key difference is cost - generic orlistat starts from £29.69 for 4 weeks (with EDM10), while Xenical costs £38.69. Both require prescription following clinical assessment and work through the same fat-blocking mechanism.
What to Expect When Orlistat Works
The fat-blocking action of orlistat may cause gastrointestinal side effects, particularly if you eat high-fat meals. These effects - including oily stools or urgent bowel movements - are actually signs the medication is working. Keeping meals low in fat (approximately 15g per meal) minimises side effects while maintaining the weight loss benefits.
Order Orlistat Online Today
Now you understand how orlistat's fat-blocking mechanism works, you can order online through our regulated service. Choose from orlistat 120mg (£15.20 for 2 weeks), Xenical 120mg (£19.35), or Alli 60mg (£26.09). All prices include 10% off with code EDM10. Following prescriber approval, we'll dispatch from our GPhC-registered pharmacy with next day delivery across the UK.
