Why Orlistat's Mechanism Makes It Effective
How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks these enzymes, approximately one third of the fat you eat cannot be digested or absorbed. This unabsorbed fat passes naturally through your body, reducing the calories you gain from dietary fat.
Why This Mechanism Is Proven to Work
Unlike appetite suppressants that act on the brain, orlistat works locally in your gut. It's not absorbed into your bloodstream in significant amounts, making it a targeted approach to weight management. The mechanism is consistent - every time you take orlistat with a meal containing fat, it blocks approximately one third of that fat from being absorbed. This predictable action helps create the calorie deficit needed for weight loss when combined with a reduced-calorie, lower-fat diet.
Orlistat vs Xenical - Same Mechanism, Different Prices
Both generic orlistat 120mg and branded Xenical 120mg contain the same active ingredient and work through identical mechanisms. Generic orlistat costs £32.99 for 4 weeks (£29.69 with EDM10) while Xenical costs £42.99 (£38.69 with EDM10). The fat-blocking mechanism is identical - you're simply choosing between cost-effectiveness and brand preference. Both require prescription following clinical assessment.
Alli 60mg - Lower Dose Mechanism
Alli contains half the dose of prescription-strength orlistat, blocking a smaller proportion of dietary fat. At 60mg, it still works through the same lipase inhibition mechanism but with reduced potency. Alli costs £28.99 for 4 weeks (£26.09 with EDM10), offering a lower-strength option for those preferring gradual introduction to fat-blocking therapy.
Order Your Orlistat Treatment Today
Now you understand how orlistat's proven mechanism blocks approximately one third of dietary fat, you can make an informed treatment choice. Complete our online clinical assessment to have your suitability reviewed by UK-licensed prescribers. With 10% off every order using code EDM10 and next day delivery available, starting your weight management journey is straightforward. Order orlistat, Xenical or Alli today from our GPhC-registered Leicester pharmacy.
