How Orlistat's Mechanism Proves It Works
How Orlistat Blocks Fat Absorption
Orlistat works through a proven mechanism that acts locally in your digestive system. It inhibits lipase enzymes responsible for breaking down dietary fat, preventing approximately one third of the fat you eat from being absorbed into your body. This unabsorbed fat passes naturally through your digestive system, reducing the calories absorbed from each meal. Unlike appetite suppressants that act on the brain, orlistat works directly where fat digestion occurs.
Why "Approximately One Third" Matters
Clinical studies demonstrate that orlistat blocks approximately one third of dietary fat absorption - not all fat. This precise mechanism means the remaining two thirds of fat is still digested normally, ensuring your body receives essential fatty acids while reducing overall calorie intake. This targeted approach explains why orlistat requires a lower-fat diet to minimise side effects and maximise weight management benefits.
Generic Orlistat vs Xenical: Same Mechanism, Different Price
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients working through the same fat-blocking mechanism. Generic orlistat offers excellent value at £32.99 for 84 capsules (4 weeks), or £29.69 with code EDM10. Xenical costs £42.99 for the same 4-week supply. The clinical effect is identical - your choice depends on personal preference and budget. Alli 60mg provides half the dose for those preferring a lower-strength starting point.
Scientific Proof in Every Dose
Each orlistat capsule contains precisely 120mg of active ingredient, calibrated to inhibit pancreatic and gastric lipases by up to 30%. This scientific precision means you can trust the mechanism works consistently with every dose. Take one capsule with each main meal containing fat, up to three times daily. The fat-blocking effect begins within hours and continues while orlistat remains in your digestive system.
Why This Mechanism Supports Weight Management
By blocking approximately one third of dietary fat absorption, orlistat can reduce calorie intake by roughly 150-200 calories per day when following a moderate-fat diet. Over time, this calorie reduction may contribute to weight management alongside your reduced-calorie eating plan and increased physical activity. The mechanism works best when combined with meals containing no more than 15g fat each.
Buy Orlistat Online with Confidence
Now you understand how orlistat's proven mechanism blocks fat absorption, you can buy with confidence from our GPhC-registered pharmacy. Complete our online clinical assessment for review by UK-licensed prescribers. Choose from 2-week supplies (42 capsules, £16.89) up to 12-week supplies (252 capsules, £95.99). Use code EDM10 for 10% off every order. Order today for next-day delivery across the UK.
