Why Orlistat's Fat-Blocking Action Drives Results
The Science: How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system - the enzymes responsible for breaking down dietary fat. When these enzymes are blocked, approximately one third of the fat you consume cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your system, effectively reducing calorie intake from dietary fat.
Unlike stimulant-based weight loss treatments that act on the brain, orlistat works locally in your gut. It's not absorbed into your bloodstream in significant amounts, making its action targeted and mechanical rather than systemic.
Orlistat vs Xenical - Same Active Ingredient, Different Price
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients at the same dose. The clinical effect is the same - both block approximately one third of dietary fat absorption. Generic orlistat offers significant savings: 4 weeks costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10).
Complete your online assessment today to access prescription-strength orlistat from our GPhC-registered pharmacy.
Dosing for Maximum Fat-Blocking Effect
Orlistat 120mg is taken as one capsule three times daily with each main meal containing fat. Take immediately before, during, or up to one hour after eating. If you skip a meal or eat a fat-free meal, you can skip that dose. Our pack sizes provide:
• 42 capsules (2 weeks): £16.89 → £15.20 with EDM10
• 84 capsules (4 weeks): £32.99 → £29.69 with EDM10
• 168 capsules (8 weeks): £63.99 → £57.59 with EDM10
• 252 capsules (12 weeks): £95.99 → £86.39 with EDM10
Why the Mechanism Matters for Your Success
Orlistat's fat-blocking mechanism provides tangible proof it's working. When you follow a lower-fat diet (approximately 15g fat per meal), side effects are minimal. Higher-fat meals result in more noticeable gastrointestinal effects - direct evidence that orlistat is blocking fat absorption as intended.
This mechanical action, combined with a reduced-calorie, lower-fat diet, may support weight management in adults with a BMI of 30 or above, or 28 or above with weight-related health conditions.
Start Your Assessment - Fast UK Delivery
Our online clinical assessment takes minutes to complete. A UK-licensed prescriber reviews your information and, if appropriate, issues your prescription. All medication is dispensed by our Leicester-based, GPhC-registered pharmacy with next-day delivery available. Use code EDM10 for 10% off every order.
