The Science Behind Why Orlistat Works
How Orlistat Blocks Fat Absorption
Orlistat works through a scientifically proven mechanism - it inhibits lipase enzymes in your digestive system that break down dietary fat. When these enzymes are blocked, approximately one third of the fat you consume cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your digestive system, reducing the calories your body takes in from fatty foods.
Why This Mechanism Proves It Works
Unlike appetite suppressants that act on your brain, orlistat works locally in your gut. This targeted approach means you can see direct evidence it's working - the unabsorbed fat is eliminated from your body. The mechanism is so reliable that orlistat has been clinically studied and approved by the MHRA for weight management in the UK.
Orlistat vs Xenical - Same Proven Mechanism
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and work through the same fat-blocking mechanism. Generic orlistat offers the same clinical effect at better value - 4-week supply from £29.69 compared to Xenical at £38.69 (both with EDM10 discount). Alli 60mg provides the same mechanism at half strength.
What You Can Expect
When taking orlistat alongside a reduced-calorie, lower-fat diet, you may experience gastrointestinal effects - these are actually signs the mechanism is working. Keeping meals to approximately 15g fat each minimises side effects while maintaining the fat-blocking effect. Most patients see the mechanism working within days of starting treatment.
Order Your Orlistat Today
Now you understand how orlistat's proven mechanism blocks approximately one third of dietary fat, order your supply today. Complete our online clinical assessment - if suitable, your prescription will be reviewed by a UK-licensed prescriber and dispensed by our GPhC-registered Leicester pharmacy. Choose from orlistat 120mg (from £15.20), Xenical 120mg (from £19.35), or Alli 60mg (from £26.09) - all with 10% off using EDM10.
