Proven Fat-Blocking Mechanism - Ready to Start Today
How Orlistat's Fat-Blocking Action Works
Orlistat works through a scientifically proven mechanism that targets lipase enzymes in your digestive system. These enzymes normally break down dietary fat for absorption. When orlistat inhibits these lipases, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your digestive system and is excreted.
This local action in the gut means orlistat isn't significantly absorbed into your bloodstream, making it different from appetite suppressants that act on the brain. The mechanism is immediate - orlistat starts blocking fat absorption from your very first dose when taken with meals containing fat.
Why This Mechanism Supports Weight Management
By blocking approximately one third of dietary fat absorption, orlistat reduces the calories your body absorbs from fatty foods. Since fat contains 9 calories per gram (compared to 4 calories per gram from carbohydrates or protein), blocking fat absorption can significantly reduce your total calorie intake when combined with a lower-fat diet.
Generic orlistat 120mg costs just £29.69 for a 4-week supply (84 capsules) with code EDM10, while branded Xenical containing the same active ingredient costs £38.69 for 4 weeks. Both work through identical fat-blocking mechanisms.
Orlistat When Trying to Conceive - Weight Management Benefits
When trying to conceive, achieving a healthy BMI can support fertility. Orlistat may help some women reach a healthier weight through its proven fat-blocking action. However, orlistat should not be used during pregnancy or while actively trying to conceive, as weight loss during pregnancy isn't recommended.
If you're planning to conceive, speak with your healthcare provider about timing your weight management programme. Many women use orlistat to achieve their target weight before trying to conceive, then stop treatment when actively trying for pregnancy.
Three Options - Same Fat-Blocking Mechanism
We offer three orlistat options, all working through the same lipase-inhibiting mechanism:
Generic Orlistat 120mg: Most cost-effective option. 12-week supply (252 capsules) costs £86.39 with EDM10 - saving over £40 compared to branded Xenical.
Xenical 120mg: Branded version by Roche. Contains identical active ingredient. 12-week supply costs £116.09 with EDM10.
Alli 60mg: Lower-strength option blocking a smaller proportion of dietary fat. 12-week supply costs £116.99 with EDM10.
Order Today - Proven Mechanism, Proven Results
Now you understand exactly how orlistat blocks approximately one third of dietary fat through lipase inhibition, you can make an informed decision. Our UK-licensed prescribers assess suitability through a comprehensive online consultation. Treatment includes prescription, medication, and next-day delivery - all from a GPhC-registered pharmacy.
Complete your clinical assessment today and get orlistat delivered discreetly to your door. Use code EDM10 for 10% off every order. Start your weight management programme with the fat-blocking power of orlistat.


