When Was Orlistat Approved? Orlistat vs Xenical UK

pricing for mounjaro and wegovy weight loss

Orlistat was first approved in 1999 as a prescription weight loss medication. Today, you can choose between generic orlistat 120mg (from £15.20 with EDM10) or branded Xenical 120mg (from £19.35 with EDM10) - both contain identical active ingredients but differ in price. Following online clinical assessment by UK-licensed prescribers, both options work by blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet. Dispensed by our GPhC-registered Leicester pharmacy with next-day delivery across the UK.

  • Same clinical effect - orlistat 120mg in both generic and Xenical versions
  • Save money with generic orlistat - up to £30 less per 12-week supply
  • Fast online prescription service - UK-licensed prescriber review included
  • Next-day delivery from GPhC-registered pharmacy with 10% off code EDM10
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Orlistat vs Xenical: Which Should You Buy?

Orlistat Approval History and Today's Options

Orlistat received regulatory approval in 1999 as the first prescription lipase inhibitor for weight management. Over 25 years later, UK patients can choose between cost-effective generic orlistat 120mg or branded Xenical 120mg - both containing identical active ingredients at the same clinical dose. Following online clinical assessment, either option may support weight management when used alongside a reduced-calorie, lower-fat diet and increased physical activity.

Generic Orlistat 120mg vs Branded Xenical 120mg

The key difference between orlistat and Xenical is price, not clinical effect. Generic orlistat 120mg costs £32.99 for a 4-week supply (£29.69 with EDM10), while branded Xenical 120mg costs £42.99 (£38.69 with EDM10) - saving you approximately £9 per month with the generic option. Both products work by inhibiting lipase enzymes to block approximately one third of dietary fat absorption, with identical dosing of one capsule three times daily with main meals containing fat.

Cost Comparison: Significant Savings Available

Our pricing demonstrates substantial savings when choosing generic orlistat over Xenical. A 12-week supply of orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10) - saving nearly £30 over three months. For patients requiring longer-term treatment, these savings become even more significant whilst receiving clinically equivalent medication dispensed by the same GPhC-registered pharmacy.

Alli 60mg: Lower-Strength Alternative

For those preferring a lower-dose option, Alli 60mg provides half the strength of prescription orlistat. At £54.99 for an 8-week supply (£49.49 with EDM10), Alli offers a gentler introduction to orlistat treatment with typically milder gastrointestinal side effects, though with reduced fat-blocking capacity compared to the 120mg prescription options.

Online Prescription Process

Both orlistat and Xenical require prescription following clinical assessment by UK-licensed prescribers. Our online consultation reviews your medical history, current medications, and BMI to determine suitability. Treatment may be appropriate for adults with BMI 30+ or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure. Once approved, medication is dispensed by our Leicester-based GPhC-registered pharmacy with next-day delivery across the UK.

Making Your Choice: Orlistat or Xenical?

Most patients choose generic orlistat for its cost-effectiveness, whilst others prefer branded Xenical. Both options provide identical clinical benefits when used correctly alongside dietary changes. Consider your budget, treatment duration, and personal preferences when deciding. Use code EDM10 for 10% off every order, making generic orlistat even more affordable at £86.39 for a 12-week supply.

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