How to Treat Cold Sores: Quick Facts & Treatment

Cold sores are common viral infections affecting up to 70% of the UK population. These fluid-filled blisters, caused by herpes simplex virus (HSV-1), typically appear around the lips and can be effectively managed with antiviral treatments. Early intervention with medications like aciclovir can help reduce both the severity and duration of outbreaks, providing faster relief from uncomfortable symptoms.

  • Start antiviral treatment within 24-48 hours of first symptoms for best results
  • Aciclovir tablets (400mg) are the most commonly prescribed oral treatment
  • Topical aciclovir cream can be applied directly to affected areas
  • Avoid touching or picking at blisters to prevent spreading infection
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Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Cold Sore.

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Aciclovir Tablets

From £12.99

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Aciclovir 5% Cream

From £8.99

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Valaciclovir

From £18.99

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Valtrex

From £34.99

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Treatment Options Available Through EverydayMeds

Understanding Cold Sore Treatment

Cold sores progress through five distinct stages, from initial tingling to complete healing over 7-10 days. The most effective treatment window occurs during the first 24-48 hours when you experience tingling, itching, or burning sensations. This is when antiviral medications like aciclovir work most effectively to limit viral replication.

Aciclovir: First-Line Treatment

Aciclovir remains the gold standard for cold sore treatment in the UK. Available as both tablets and topical cream, aciclovir works by preventing the herpes virus from reproducing. EverydayMeds offers aciclovir 400mg tablets for systemic treatment and aciclovir 5% cream for localised application. The typical oral dosage involves taking 400mg three times daily for five days, though treatment duration may vary based on individual response.

Alternative Antiviral Options

For patients who may not respond optimally to aciclovir, valaciclovir represents an effective alternative. Valaciclovir 500mg tablets, including the branded Valtrex formulation, offer improved bioavailability and may require less frequent dosing. This can be particularly beneficial for managing recurrent outbreaks or for patients with compliance concerns regarding multiple daily doses.

When to Seek Treatment

Consider prescription antiviral treatment if you experience frequent outbreaks (more than six per year), severe symptoms, or if cold sores significantly impact your quality of life. Immunocompromised individuals should seek prompt medical attention for any herpes virus infection. EverydayMeds provides convenient access to prescription treatments following appropriate medical consultation.

Supporting Recovery

Alongside antiviral medication, several measures can support healing and prevent transmission. Keep the affected area clean and dry, avoid touching blisters, and wash hands frequently. Consider using separate towels and utensils during active outbreaks. Some patients find that identifying and avoiding personal triggers helps reduce outbreak frequency.

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