Prescription Antiviral Treatments for Cold Sores
Aciclovir Tablets: First-Line Treatment
Aciclovir 400mg tablets represent the most widely prescribed antiviral treatment for cold sores in the UK. This medication works by inhibiting viral DNA replication, effectively stopping the herpes simplex virus from multiplying. For maximum effectiveness, treatment should commence within 24 hours of symptom onset, ideally at the first tingling sensation.
Treatment Regimens and Effectiveness
The standard aciclovir dosage for cold sores is 400mg taken five times daily for five days. Clinical studies demonstrate that early intervention can reduce healing time by 1-2 days and decrease pain severity. Valaciclovir 500mg tablets offer an alternative with twice-daily dosing, which may improve treatment adherence for some patients.
Topical Antiviral Options
Aciclovir 5% cream provides localised treatment when applied every four hours during waking hours. Whilst topical treatments generally show modest benefits compared to oral therapy, they may suit patients who prefer external application or cannot tolerate oral antivirals.
Supporting Lip Care Measures
Beyond antiviral treatment, proper lip care helps minimise discomfort and prevent secondary bacterial infection. Keep the affected area clean and dry, avoid touching or picking at blisters, and apply protective lip balm with SPF 15 or higher to prevent sun-triggered recurrences. Cold compresses may provide symptomatic relief during the painful blister stage.
When to Seek Professional Advice
Consult healthcare professionals if outbreaks occur frequently (more than six episodes annually), if symptoms are severe, or if you have compromised immunity. Suppressive antiviral therapy may be appropriate for frequent recurrences, typically involving daily aciclovir or valaciclovir to reduce outbreak frequency.
