Common Side Effects and Management Strategies
Understanding Aciclovir Side Effects
Aciclovir tablets, the primary treatment for cold sores available through EverydayMeds, are generally well-tolerated. However, some patients may experience mild side effects including nausea, headache, diarrhoea, or fatigue. These effects typically resolve as your body adjusts to the medication. Taking tablets with food can significantly reduce gastrointestinal symptoms, whilst maintaining adequate hydration helps prevent headaches.
Gastrointestinal Management
Stomach upset is the most reported side effect of oral aciclovir. To minimise nausea and stomach discomfort, take your prescribed dose with meals or a snack. Avoid spicy or acidic foods during treatment, as these may worsen stomach irritation. If diarrhoea occurs, maintain fluid intake and consider probiotics to support digestive health. Persistent gastrointestinal symptoms warrant medical review.
Neurological Side Effects
Some patients experience headaches, dizziness, or fatigue whilst taking aciclovir tablets. Ensuring adequate hydration often alleviates headaches, as dehydration can exacerbate this side effect. If dizziness occurs, avoid driving or operating machinery until symptoms resolve. Fatigue typically improves after the first few days of treatment. Contact your prescriber if neurological symptoms worsen or persist beyond the treatment course.
Skin Reactions and Allergic Responses
Whilst uncommon, some individuals may develop skin rashes or allergic reactions to aciclovir. Mild skin reactions may manifest as itching or localised rash. However, if you develop widespread rash, difficulty breathing, or facial swelling, discontinue treatment immediately and seek urgent medical attention. EverydayMeds offers alternative antiviral options like valaciclovir for patients who cannot tolerate aciclovir.
When to Seek Medical Advice
Most side effects from aciclovir are manageable and temporary. However, contact your healthcare provider if you experience severe or persistent symptoms, signs of kidney problems (reduced urination, swelling), or any concerning changes in your health during treatment. Our clinical team at EverydayMeds can provide guidance on managing side effects whilst ensuring effective cold sore treatment.






