Complete Aciclovir Dosage and Administration Guide
Understanding Cold Sores and Herpes Treatment
Cold sores are caused by herpes simplex virus type 1 (HSV-1), affecting up to 70% of the UK population. Aciclovir works by preventing the virus from reproducing, which can help reduce outbreak severity and duration. EverydayMeds stocks aciclovir 400mg tablets alongside topical treatments for comprehensive cold sore management.
How to Take Aciclovir Tablets Correctly
The typical adult dosage for cold sores is 400mg taken five times daily for five days. This means taking one tablet approximately every four hours while awake. Tablets should be swallowed whole with water and can be taken with or without food. Starting treatment within 24-48 hours of symptom onset typically provides the best results.
Timing Your Treatment for Maximum Effectiveness
Early intervention is crucial for aciclovir effectiveness. Begin treatment as soon as you notice the first tingling, itching, or burning sensations that precede visible cold sores. Some people recognise these prodromal symptoms and can start treatment before blisters appear, potentially preventing full outbreak development.
Treatment Duration and Course Completion
Complete the full five-day course even if symptoms improve earlier. Stopping treatment prematurely may allow the virus to continue replicating. Each tablet contains 400mg of aciclovir, and maintaining consistent levels in your system helps suppress viral activity throughout the outbreak period.
Alternative Treatment Options
EverydayMeds also offers valaciclovir tablets, which require less frequent dosing, and aciclovir cream for topical application. Some patients benefit from combination approaches using both oral and topical treatments, though this should be discussed with your prescriber.
What to Expect During Treatment
Most people tolerate aciclovir well, with treatment potentially reducing outbreak duration from 7-10 days to 4-6 days. Common mild side effects may include headache or nausea. If you experience severe reactions or symptoms worsen, consult your healthcare provider promptly.






