When to Start Aciclovir Treatment: MHRA Guidelines
Critical Timing Window for Aciclovir
The MHRA emphasises that aciclovir treatment should commence as early as possible, ideally within 48 hours of symptom onset. Research shows that starting treatment during the prodromal stage (tingling, burning sensation) can reduce outbreak duration by 1-2 days and decrease symptom severity.
Recognising Early Warning Signs
Cold sore symptoms typically follow a predictable pattern. The prodromal phase begins 12-24 hours before visible blisters appear, presenting as tingling, itching, or burning sensations around the lips or mouth area. This is the optimal window for starting aciclovir treatment.
Aciclovir Dosing Schedule
For cold sores, the standard aciclovir regimen involves 400mg tablets taken five times daily for five consecutive days. This frequent dosing schedule maintains therapeutic drug levels necessary for viral suppression. EverydayMeds stocks both aciclovir tablets and topical formulations to suit different treatment preferences.
Treatment Options at EverydayMeds
Our online pharmacy offers various aciclovir formulations including 400mg tablets for systemic treatment and 5% cream for topical application. Valaciclovir 500mg tablets provide an alternative with less frequent dosing requirements. All treatments require proper medical assessment through our online consultation service.
Maximising Treatment Effectiveness
Consistent dosing intervals are essential for maintaining antiviral effectiveness. Set regular reminders to ensure doses are not missed, particularly during the first 48 hours when viral replication is most active. Complete the full course even if symptoms resolve early to prevent treatment resistance.






