Choose Your Orlistat Weight Loss Treatment
Metformin vs Orlistat: Key Differences for Weight Loss
When comparing metformin vs orlistat for weight management, it's important to understand that these medications work very differently. Metformin is primarily a diabetes medication that may have some weight-related effects, whilst orlistat is specifically licensed for weight management in UK adults. Orlistat works by blocking approximately one third of dietary fat absorption in the gut, helping reduce calorie intake when used alongside a reduced-calorie, lower-fat diet and increased physical activity.
Why Choose Orlistat for Weight Management?
Orlistat is the UK's leading prescription weight loss treatment, available in three forms at EverydayMeds. Generic orlistat 120mg offers excellent value at £32.99 for a 4-week supply (£29.69 with EDM10), whilst branded Xenical 120mg provides the same clinical effect at £42.99 (£38.69 with EDM10). For those preferring a lower-strength option, Alli 60mg is available from £28.99 for 4 weeks (£26.09 with EDM10). All products may help support weight management when combined with dietary and lifestyle changes.
How Orlistat Works Differently from Metformin
Unlike metformin, which primarily affects blood sugar metabolism, orlistat works locally in the digestive system by inhibiting lipase enzymes. This prevents approximately one third of dietary fat from being absorbed, with unabsorbed fat passing naturally through the body. Orlistat is specifically indicated for adults with a BMI of 30 or above, or BMI 28 or above with weight-related health conditions. Start your online consultation to see if orlistat is suitable for your weight management goals.
Complete Orlistat Treatment Options
EverydayMeds offers flexible treatment durations to suit your needs. Choose from 2-week starter packs (42 capsules at £16.89), 4-week supplies (84 capsules at £32.99), 8-week courses (168 capsules at £63.99), or 12-week programmes (252 capsules at £95.99). All prices include 10% discount with code EDM10. Xenical and Alli are also available in multiple pack sizes. Our UK-licensed prescribers will assess your suitability through a comprehensive online consultation, with next day delivery available across the UK.


