Choose Your Prescription Weight Loss Treatment
Orlistat vs Mysimba: Understanding Your Options
When considering prescription weight loss treatment in the UK, orlistat and Mysimba represent two different approaches to supporting weight management. Orlistat works by blocking approximately one third of dietary fat absorption in the gut, whilst Mysimba combines naltrexone and bupropion to help reduce appetite and food cravings. Both require a prescription following clinical assessment and work best alongside a structured diet and exercise programme.
Orlistat 120mg: Fat Absorption Blocker
Orlistat 120mg capsules work locally in the digestive system by inhibiting lipase enzymes that break down dietary fat. This means approximately one third of the fat you eat passes through the body unabsorbed. Available as generic orlistat from £29.69 for 4 weeks (84 capsules) or branded Xenical from £38.69 for the same period with EDM10 discount code. The lower-strength Alli 60mg is also available from £26.09 for 4 weeks.
Which Treatment May Be Right for You?
Your prescriber will assess which treatment is most suitable based on your individual health circumstances, BMI, medical history, and weight-related health factors. Orlistat may be suitable for adults with a BMI of 30 kg/m² or above, or 28 kg/m² with weight-related conditions like type 2 diabetes or high blood pressure. Mysimba has different eligibility criteria and contraindications that your prescriber will review during consultation.
Cost Comparison and Treatment Duration
Orlistat pricing starts from £15.20 for 2 weeks, making it one of the most cost-effective prescription weight loss options. Longer treatment courses offer better value - 12-week supplies cost £86.39 for generic orlistat or £116.09 for branded Xenical with EDM10. Your prescriber may recommend a specific treatment duration based on your weight management goals and response to treatment.
The Online Prescription Process
Complete a confidential health questionnaire covering your medical history, current medications, and weight management goals. A UK-licensed prescriber reviews your information and determines treatment suitability. If appropriate, your prescription is dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address. The prescription is included in the price - no separate GP appointment needed.
Supporting Your Weight Loss Journey
Whether prescribed orlistat or Mysimba, success depends on combining treatment with a reduced-calorie diet and increased physical activity. Orlistat works best with a lower-fat diet (approximately 15g fat per meal) to minimise gastrointestinal side effects. Regular monitoring and ongoing support help ensure you get the best results from your prescription weight loss treatment.
Start Your Assessment Today
Take the first step towards medically-supervised weight loss. Our online consultation takes just minutes to complete, and approved prescriptions are dispatched the same day for next-day delivery. Use code EDM10 for 10% off every order. Begin your confidential assessment now and discover which prescription weight loss treatment may be right for you.


