Which Should You Choose: Generic or Branded Orlistat?
Orlistat vs Xenical: The Clinical Facts
Both orlistat 120mg and Xenical 120mg contain exactly the same active ingredient at identical doses. Clinically, they work identically - blocking approximately one third of dietary fat from being absorbed in your digestive system. The unabsorbed fat passes naturally through your body, which may support weight management when combined with a reduced-calorie, lower-fat diet and increased physical activity.
Price Comparison: Orlistat vs Xenical at EverydayMeds
Generic orlistat offers significant savings compared to branded Xenical. For a 4-week supply (84 capsules), orlistat costs £32.99 (£29.69 with EDM10), whilst Xenical costs £42.99 (£38.69 with EDM10). Over 12 weeks, you could save over £30 by choosing generic orlistat at £95.99 versus Xenical at £128.99. Both options are available following clinical assessment by our UK-licensed prescribers.
Alternative Option: Alli 60mg
For those preferring a lower-strength starting point, Alli 60mg contains half the dose of prescription-strength orlistat. At £28.99 for a 4-week supply (£26.09 with EDM10), Alli may be suitable for adults seeking a gentler introduction to orlistat treatment, though it blocks a smaller proportion of dietary fat compared to the 120mg prescription versions.
How Both Products Work
Whether you choose orlistat or Xenical, the mechanism is identical. Both inhibit lipase enzymes in your gut, preventing approximately one third of dietary fat from being digested and absorbed. This reduction in fat absorption may contribute to weight loss when used alongside appropriate dietary and lifestyle changes. The medication acts locally in your digestive system and is not significantly absorbed into your bloodstream.
Side Effects: What to Expect
Both orlistat and Xenical may cause identical gastrointestinal side effects, including oily stools, increased bowel movements, and abdominal discomfort. These effects are more likely when eating high-fat meals and can be minimised by keeping each meal to approximately 15g of fat. Most patients find side effects reduce as they adapt to a lower-fat diet.
Getting Your Prescription Online
Our streamlined process makes accessing either orlistat or Xenical straightforward. Complete our online health questionnaire, which is reviewed by a UK-licensed prescriber. If treatment is deemed appropriate following clinical assessment, your prescription is dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly to your address with next day delivery available.
Making Your Decision
Choose generic orlistat if you prioritise value - you'll receive clinically identical treatment at the lowest cost. Choose Xenical if you prefer the branded option from Roche. Both require the same commitment to a reduced-calorie, lower-fat diet and regular physical activity. Use code EDM10 for 10% off either option, available to new and returning customers.


