Orlistat vs Xenical: Which Should You Buy in the UK?

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Orlistat 120mg and Xenical 120mg contain identical active ingredients and deliver the same clinical effect. The key difference is cost: generic orlistat starts from £15.20 (with EDM10) versus Xenical from £19.35 for the same 2-week supply. Both are prescription-only medicines that work by blocking approximately one third of dietary fat absorption. Following an online clinical assessment by UK-licensed prescribers, you can access both options through our GPhC-registered pharmacy with next day delivery. Use code EDM10 for 10% off every order.

  • Same active ingredient - orlistat 120mg in both products
  • Generic orlistat saves £9+ per month versus branded Xenical
  • Both require prescription following clinical assessment
  • Next day delivery from GPhC-registered UK pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Compare Orlistat vs Xenical Prices and Make Your Choice

Orlistat 120mg vs Xenical 120mg: The Facts

When choosing between orlistat and Xenical in the UK, you're comparing two clinically equivalent medicines. Both contain orlistat 120mg as the active ingredient and work identically by blocking approximately one third of dietary fat absorption. The primary difference lies in cost and branding - generic orlistat offers the same therapeutic effect at a significantly lower price point.

Price Comparison: Orlistat vs Xenical UK

Our pricing demonstrates clear savings with generic orlistat. For a 4-week supply (84 capsules), generic orlistat costs £29.69 with code EDM10, while branded Xenical costs £38.69 - saving you £9 per month. Over a 12-week treatment period, you could save £29.70 by choosing generic orlistat (£86.39) instead of Xenical (£116.09). Both options are dispensed by our GPhC-registered pharmacy following prescriber approval.

Which Should You Choose?

The choice between orlistat and Xenical often comes down to personal preference and budget. Some patients prefer the assurance of the original branded Xenical manufactured by Roche, while others choose generic orlistat for better value without compromising clinical effectiveness. Both require the same reduced-calorie, lower-fat diet alongside treatment and carry identical side effect profiles.

Alternative: Alli 60mg Lower-Strength Option

For those considering a lower-strength starting point, Alli 60mg provides half the dose of prescription orlistat. At £26.09 for a 4-week supply (with EDM10), Alli offers an intermediate option between no treatment and full-strength prescription orlistat or Xenical.

How to Order Orlistat or Xenical Online

Both medicines require prescription following an online clinical assessment. Complete our medical questionnaire, which will be reviewed by a UK-licensed prescriber. If treatment is deemed clinically appropriate, your chosen option will be dispensed and dispatched for next day delivery. The prescription is included in the price - no separate GP appointment needed.

Clinical Considerations for Both Options

Whether you choose orlistat or Xenical, both may be suitable for adults with a BMI of 30kg/m² or above, or 28kg/m² with weight-related health conditions. Treatment works best when combined with a structured weight management programme including dietary changes and increased physical activity. Most side effects are gastrointestinal and can be minimised by keeping dietary fat intake low.

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