Which Should You Choose: Generic or Branded?
Orlistat vs Xenical: Clinical Equivalence
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients at the same dose. Clinically, they work in exactly the same way - blocking approximately one third of dietary fat absorption in your gut. Neither product affects the liver directly, as orlistat acts locally in the digestive system and is not significantly absorbed into the bloodstream. Following clinical assessment by a UK-licensed prescriber, either option may be suitable for weight management alongside a reduced-calorie, lower-fat diet.
Price Comparison: Significant Savings Available
The main difference between these treatments is cost. Generic orlistat offers substantial savings: 4-week supply costs £32.99 (£29.69 with EDM10) compared to Xenical at £42.99 (£38.69 with EDM10). Over 12 weeks, you could save over £29 choosing generic orlistat at £95.99 (£86.39 with EDM10) versus Xenical at £128.99 (£116.09 with EDM10). Both options require the same prescription process and clinical assessment.
Liver Safety Considerations
Concerns about orlistat and liver damage are rare but important to understand. Both orlistat and Xenical carry the same safety profile, including very rare reports of liver problems. Our prescribers assess your individual health circumstances, including liver function, during the online consultation. If you have existing liver conditions or take medications affecting the liver, this will be reviewed as part of your clinical assessment. Most patients can use orlistat safely when prescribed appropriately.
Alli 60mg: Lower-Strength Alternative
For those preferring a gentler approach, Alli 60mg provides half the dose of prescription-strength orlistat. At £28.99 for 4 weeks (£26.09 with EDM10), Alli blocks a smaller proportion of dietary fat, typically resulting in milder gastrointestinal side effects. While less potent than the 120mg options, Alli can support weight management for some patients and doesn't require a prescription.
Making Your Decision
Choose generic orlistat 120mg for maximum value while maintaining clinical effectiveness. Choose Xenical if you prefer the branded option and don't mind paying extra. Choose Alli 60mg if you want a lower-strength starting point. All options work by the same mechanism and can support weight management when used alongside dietary changes. Complete our online assessment to determine which treatment suits your needs and budget.
Order Process: Simple and Discreet
Complete an online health questionnaire reviewed by our UK-licensed prescribers. If treatment is deemed appropriate, your chosen medication is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address. Next-day delivery available across the UK. Use code EDM10 for 10% off every order. Start your consultation today and compare both options during the assessment process.


