Why Understanding the Mechanism Matters for Your Choice
How Orlistat's Fat-Blocking Mechanism Works
Orlistat works through a scientifically proven mechanism that directly targets dietary fat absorption. When you eat, enzymes called lipases break down fat so your body can absorb it. Orlistat inhibits these lipase enzymes in your gut, preventing approximately one third of the fat you eat from being digested and absorbed. This unabsorbed fat passes naturally through your digestive system, reducing the calories your body takes in from dietary fat.
Why All Three Products Work the Same Way
Whether you choose generic orlistat 120mg (£32.99 for 4 weeks, £29.69 with EDM10), branded Xenical 120mg (£42.99 for 4 weeks, £38.69 with EDM10), or Alli 60mg (£28.99 for 4 weeks, £26.09 with EDM10), the mechanism remains identical. The 120mg prescription versions block the same proportion of dietary fat, while Alli's lower 60mg dose provides a gentler introduction to fat-blocking treatment. All work locally in your digestive system without significant absorption into your bloodstream.
Evidence the Mechanism Actually Works
The fat-blocking mechanism isn't just theory - patients often notice unabsorbed fat being eliminated naturally, particularly when eating higher-fat meals. This visible proof demonstrates the medicine is actively working. The mechanism is most effective when combined with a reduced-calorie, lower-fat diet, as keeping fat intake to approximately 15g per meal minimises side effects while maximising the treatment benefit.
Choosing Based on Mechanism Understanding
Now you understand how orlistat blocks fat absorption, you can make an informed choice between the three options. Generic orlistat 120mg offers the most cost-effective access to the full prescription-strength mechanism. Xenical 120mg provides the same clinical effect with branded assurance. Alli 60mg delivers the proven mechanism at half strength for those preferring a gentler start.
Ready to Order Your Fat-Blocking Treatment
Understanding the mechanism proves orlistat's effectiveness - it's not just an appetite suppressant but actively prevents dietary fat absorption. Our 8-week supply of orlistat costs just £57.59 with code EDM10, while 12-week supplies provide the best value at £86.39. Complete your online clinical assessment today and have your chosen treatment delivered discreetly tomorrow by our GPhC-registered pharmacy in Leicester.


