Orlistat vs Xenical: Which Should You Choose?
How Orlistat Works – Not an Appetite Suppressant
Orlistat works differently to appetite suppressants. Instead of affecting your brain or hunger signals, orlistat acts locally in your digestive system by inhibiting lipase enzymes. This blocks approximately one third of the fat you eat from being absorbed, with unabsorbed fat passing naturally through your body. Whether you choose generic orlistat or branded Xenical, the mechanism is identical.
Orlistat 120mg vs Xenical 120mg: The Facts
Generic orlistat 120mg and Xenical 120mg are clinically equivalent. Both contain orlistat 120mg as the active ingredient and work identically to reduce dietary fat absorption. The only meaningful difference is cost – choosing generic orlistat can save you approximately £9 per month compared to Xenical. Our 4-week supply costs £29.69 for orlistat vs £38.69 for Xenical (with EDM10 discount).
Pricing Comparison: Orlistat vs Xenical
Orlistat 120mg pricing: 2 weeks (42 capsules) £15.20, 4 weeks (84 capsules) £29.69, 8 weeks (168 capsules) £57.59, 12 weeks (252 capsules) £86.39 with EDM10. Xenical 120mg pricing: 2 weeks £19.35, 4 weeks £38.69, 8 weeks £78.29, 12 weeks £116.09 with EDM10. Both require the same online clinical assessment and prescription from our UK-licensed prescribers.
Alternative: Alli 60mg Lower Strength
Alli 60mg contains half the dose of prescription orlistat, blocking a smaller proportion of dietary fat. Available as 4 weeks (42 capsules) £26.09, 8 weeks (84 capsules) £49.49, 12 weeks (252 capsules) £116.99 with EDM10. Alli may be suitable for those preferring a lower-strength starting point with typically milder gastrointestinal side effects.
Online Prescription Process
Complete our online health questionnaire covering your medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment and issues a prescription where clinically appropriate. Your chosen treatment is then dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly next day. The prescription is included in the price – no separate GP appointment needed.
Order Today with 10% Off
Whether you choose cost-effective generic orlistat or branded Xenical, save 10% on every order with code EDM10. Both work identically to support weight management alongside a reduced-calorie, lower-fat diet. Start your clinical assessment today for next day delivery from our regulated UK online pharmacy.


