Orlistat vs Xenical: Clinical Equivalence, Cost Difference
Are Orlistat and Xenical the Same Medicine?
Orlistat 120mg and Xenical 120mg are clinically equivalent medicines containing the same active ingredient at identical doses. The only meaningful difference is cost – generic orlistat offers the same clinical effect as branded Xenical at a significantly lower price. Both work by blocking approximately one third of dietary fat absorption and require a prescription following clinical assessment by a UK-licensed healthcare professional.
Private Prescription Route – Faster Than NHS
Skip NHS waiting lists with EverydayMeds' private prescription service. Our UK-licensed prescribers review applications quickly, often within hours rather than weeks. Complete an online clinical assessment from home – no GP appointment needed. Once approved, your prescription is dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly to your address.
Cost Comparison: Significant Savings with Generic
Generic orlistat 120mg costs £32.99 for 4 weeks (£29.69 with EDM10), whilst branded Xenical costs £42.99 (£38.69 with EDM10). That's approximately £9 monthly savings choosing generic orlistat. For 12-week supplies, orlistat costs £95.99 (£86.39 with EDM10) compared to Xenical at £128.99 (£116.09 with EDM10) – saving nearly £30. Use code EDM10 for 10% off every order.
How Both Products Work
Whether you choose generic orlistat or branded Xenical, the mechanism is identical. Both inhibit lipase enzymes in the gut to prevent approximately one third of dietary fat from being absorbed. Unabsorbed fat passes naturally through the body. Both must be used alongside a reduced-calorie, lower-fat diet and work best when fat intake is kept to around 15g per meal to minimise gastrointestinal side effects.
Who Can Access Private Prescriptions?
Private prescriptions may be suitable for adults with a BMI of 30 or above, or BMI 28+ with weight-related health conditions like type 2 diabetes or high blood pressure. Your prescriber will assess eligibility based on your individual health circumstances. The online consultation covers medical history, current medications, and weight management goals to determine if orlistat treatment is appropriate.
Order Process and Delivery
Complete our online health questionnaire in minutes. A UK-licensed prescriber reviews your application and issues a prescription where clinically appropriate. Our GPhC-registered pharmacy dispenses your order using MHRA-regulated stock. Next day delivery is available across the UK with tracked, discreet packaging. Your prescription is included in the price – no separate consultation fees.


