Understanding Orlistat vs GLP-1 Weight Loss Options
What is Orlistat and How Does it Differ from GLP-1?
Orlistat is not a GLP-1 medication. While GLP-1 treatments are injectable hormones that work on brain appetite centres, orlistat is an oral fat-blocking treatment that works locally in your digestive system. Orlistat 120mg capsules inhibit lipase enzymes to prevent approximately one third of dietary fat from being absorbed. This unabsorbed fat passes naturally through your body, supporting weight management when used alongside a reduced-calorie, lower-fat diet.
Orlistat Pricing and Options at EverydayMeds
Generic orlistat 120mg offers excellent value: 4-week supply £32.99 (£29.69 with EDM10), 8-week supply £63.99 (£57.59 with EDM10), 12-week supply £95.99 (£86.39 with EDM10). Branded Xenical 120mg contains identical active ingredient: 4-week supply £42.99 (£38.69 with EDM10). Alli 60mg lower-strength option: 8-week supply £54.99 (£49.49 with EDM10). Use code EDM10 for 10% off every order.
How Our Online Prescription Process Works
Complete our online health questionnaire covering medical history, current medications, and BMI information. A UK-licensed prescriber reviews your assessment to determine if orlistat is clinically appropriate. Unlike GLP-1 treatments requiring specialist clinics, orlistat can be prescribed through our regulated online service. Once approved, your prescription is dispensed by our GPhC-registered Leicester pharmacy with next day delivery available across the UK.
Who May Be Suitable for Orlistat Treatment?
Orlistat may be suitable for adults with BMI 30kg/m² or above, or BMI 28kg/m² with weight-related health conditions like type 2 diabetes or high blood pressure. Unlike GLP-1 medications, orlistat works regardless of diabetes status. Your prescriber will assess individual suitability during the clinical review. Treatment must be combined with a structured lower-fat diet and increased physical activity for optimal results.
Managing Treatment and What to Expect
Take one 120mg capsule with each main meal containing fat, up to three times daily. Unlike GLP-1 injections with potential nausea, orlistat's main side effects are gastrointestinal and directly related to dietary fat intake. Keeping meals low in fat (approximately 15g per meal) significantly reduces side effects while maintaining effectiveness. Most patients find side effects decrease as they adapt to a healthier, lower-fat eating pattern.


