Promethazine BNF Dosage & Administration Guide

Promethazine (Phenergan) is a sedating antihistamine used for allergies, sleep problems, and nausea. Proper dosing is essential for safe, effective treatment. This BNF-based guide covers correct administration for tablets and liquid forms. EverydayMeds stocks Phenergan 25mg tablets and 5mg/5ml elixir to support various treatment needs. Always follow prescribed dosing schedules and medical guidance for optimal results.

  • Take tablets with water, with or without food
  • Measure liquid doses accurately using provided spoon
  • Evening dosing reduces daytime drowsiness risk
  • Never exceed maximum daily dose limits
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Available Treatments

Choose between Phenergan tablets or Phenergan elixir to suit your needs, and buy online for fast, effective relief from allergies, motion sickness, and short-term sleep difficulties.

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Phenergan 25mg (Promethazine Hydrochloride) - 56 Tablets

£14.99

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Phenergan Elixir 5mg/5ml Oral Solution – 100ml

£14.49

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Promethazine Dosing Schedule & Administration

Standard Adult Dosing Guidelines

For allergic conditions, promethazine tablets are typically taken as 25mg at bedtime, or divided doses of 10-20mg taken 2-3 times daily. The sedating effects make evening administration preferable for most patients. Sleep-related use involves 25-50mg at bedtime for short-term treatment only.

Liquid Formulation Administration

Phenergan elixir (5mg/5ml) offers flexible dosing options, particularly useful when precise dose adjustments are needed. Adults typically take 5-10ml as directed by healthcare providers. Always use the measuring device provided to ensure accurate dosing. The liquid can be taken directly or mixed with water if preferred.

Motion Sickness Prevention

For travel sickness, take 25mg the evening before travel, followed by 25mg on the morning of departure. Additional doses may be taken during long journeys if needed, following medical guidance on timing intervals.

Important Administration Considerations

Promethazine can be taken with or without food, though taking with food may reduce potential stomach irritation. Avoid alcohol whilst taking this medication as it can increase drowsiness effects. The sedating properties typically begin within 1-2 hours of administration and can last 6-8 hours.

Dosing Frequency Guidelines

Maximum daily doses should not be exceeded: adults should not take more than 100mg in 24 hours. Space doses evenly throughout the day when multiple administrations are prescribed. For intermittent use, take only when symptoms require treatment rather than routinely.

EverydayMeds Product Options

EverydayMeds provides both Phenergan 25mg tablets (56-tablet pack) and Phenergan elixir 5mg/5ml solution (100ml bottle). These formulations offer treatment flexibility for various conditions including allergies, sleep disturbances, and motion sickness, ensuring patients can access appropriate promethazine preparations through our online pharmacy service.

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Frequently asked questions