Aciclovir Dosage and Administration Instructions
Standard Dosage for Cold Sores
The typical prescription for aciclovir tablets in treating cold sores is 200mg taken five times daily for five days, or 400mg taken three times daily for five days. Your healthcare provider will determine the most appropriate dosing schedule based on your individual circumstances and medical history.
When to Start Treatment
Aciclovir is most effective when started within 72 hours of the first symptoms appearing, ideally at the very first sign of tingling, itching, or burning around the lips. Early intervention may help reduce both the severity and duration of the outbreak. If you experience recurrent cold sores, your doctor may prescribe aciclovir to keep on hand for immediate use when symptoms begin.
How to Take Aciclovir Tablets
Swallow aciclovir tablets whole with a full glass of water. The tablets can be taken with or without food, though some people find taking them with meals helps reduce potential stomach upset. Space your doses evenly throughout the day to maintain consistent levels of the medication in your system. If you're prescribed the five-times-daily regimen, aim to take doses approximately every four hours whilst awake.
Important Considerations
Complete the full prescribed course of aciclovir even if your cold sore symptoms improve before finishing all tablets. Stopping treatment early may allow the virus to become active again. Stay well hydrated whilst taking aciclovir by drinking plenty of fluids throughout the day. EverydayMeds offers aciclovir 400mg tablets and other antiviral treatments for cold sores, available through our online consultation service with qualified healthcare professionals.
Missed Doses and Safety
If you miss a dose, take it as soon as you remember unless it's nearly time for your next scheduled dose. Never take a double dose to make up for a forgotten tablet. Contact your healthcare provider if you experience any concerning side effects or if your cold sore doesn't begin to improve within a few days of starting treatment.






