Why Orlistat's Mechanism Makes It Work for You
How Orlistat Blocks Fat Absorption
Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks approximately one third of these enzymes, that proportion of fat passes through undigested and is eliminated naturally. This mechanism reduces calorie intake from fat without affecting your brain or metabolism.
When to Take Orlistat for Maximum Effect
Take one 120mg capsule with each main meal containing fat - breakfast, lunch, and dinner. The timing is crucial: take immediately before, during, or up to one hour after eating. If you skip a meal or eat something fat-free, skip that dose. At EverydayMeds, generic orlistat 84 capsules (4-week supply) costs £29.69 with EDM10, while Xenical costs £38.69 - both containing identical 120mg orlistat.
Why the Gut-Based Mechanism Works
Unlike appetite suppressants that act on the brain, orlistat works locally in your digestive system. Only minimal amounts enter your bloodstream. This targeted action means the unabsorbed fat - approximately one third of what you eat - is eliminated through normal bowel movements. This visible proof shows the medication is working effectively.
Optimising Results with Lower-Fat Meals
The mechanism works best when each meal contains around 15g fat or less. Higher fat meals increase gastrointestinal effects as more unabsorbed fat passes through your system. Spreading fat intake evenly across three meals maximises absorption blocking while minimising side effects. A multivitamin taken at bedtime helps replace fat-soluble vitamins.
Order Orlistat Online Today
Now you understand how orlistat's proven mechanism blocks approximately one third of dietary fat, you can access this prescription medication through our online clinical assessment. Our 8-week supply (168 capsules) provides excellent value at £57.59 for generic orlistat or £78.29 for Xenical with code EDM10. Complete your assessment today for next-day delivery from our GPhC-registered pharmacy in Leicester.


