Why Understanding Orlistat's Mechanism Matters
How Orlistat Creates Its Weight Loss Effect
Orlistat works through a targeted mechanism that inhibits lipase enzymes in your digestive system. These enzymes normally break down dietary fat so your body can absorb it. When orlistat blocks these enzymes, approximately one third of the fat you eat cannot be digested or absorbed. This unabsorbed fat passes naturally through your body, reducing your calorie intake from dietary fat.
Why Stomach Cramps Occur - The Science
Stomach cramps and other gastrointestinal effects happen because unabsorbed fat moves through your digestive system. When you eat a high-fat meal while taking orlistat, more fat remains undigested, which can cause abdominal discomfort, cramping, and other gut-related side effects. These effects are actually evidence that orlistat is working exactly as designed - blocking fat absorption.
Minimising Cramps While Maximising Results
The key to reducing stomach cramps is controlling your fat intake. Keep each meal to approximately 15g of fat or less, spreading your daily fat intake evenly across three main meals. This approach helps minimise side effects while allowing orlistat to work effectively. At EverydayMeds, our 4-week orlistat supply costs £32.99 (£29.69 with EDM10), giving you time to adjust your diet and reduce cramping.
Generic Orlistat vs Xenical - Same Mechanism, Better Value
Both generic orlistat 120mg and branded Xenical 120mg contain identical active ingredients and work through the same fat-blocking mechanism. The clinical effect is identical - both block approximately one third of dietary fat absorption. Generic orlistat offers significant savings: 8 weeks costs £63.99 (£57.59 with EDM10) compared to Xenical at £86.99 (£78.29 with EDM10). Same mechanism, same results, better value.
Order Today - Put The Science To Work
Now you understand how orlistat works and why stomach cramps occur, you can make an informed decision about your weight management. Our online clinical assessment takes minutes, and if suitable, your prescription orlistat can be delivered tomorrow. Choose your supply: 12-week generic orlistat costs £95.99 (£86.39 with EDM10), dispensed by our GPhC-registered Leicester pharmacy. Complete your assessment now.


