Cold Sores and Fever Blisters: Early Treatment Guide

Cold sores and fever blisters are caused by the herpes simplex virus type 1 (HSV-1), affecting up to 70% of the UK population. Early recognition and prompt treatment with antiviral medications like aciclovir can significantly reduce symptoms and healing time. Understanding the warning signs and having treatment readily available may help manage outbreaks more effectively when they occur.

  • Initial tingling or burning sensation around the lips signals the start
  • Antiviral treatment works best when started within 24-48 hours
  • Aciclovir tablets or cream can reduce outbreak duration and severity
  • Stress, illness, or sun exposure commonly trigger recurrent episodes
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Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Cold Sore.

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Aciclovir Tablets

From £12.99

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Aciclovir 5% Cream

From £8.99

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Valaciclovir

From £18.99

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Valtrex

From £34.99

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Recognising Cold Sore Symptoms and Treatment Options

What Causes Cold Sores and Fever Blisters?

Cold sores are caused by herpes simplex virus type 1 (HSV-1), a common virus that remains dormant in nerve cells after initial infection. The virus can reactivate due to various triggers including stress, fatigue, illness, hormonal changes, or sun exposure. Once reactivated, it travels along nerve pathways to the skin surface, typically around the mouth and lips.

Early Warning Signs

The first stage involves a characteristic tingling, burning, or itching sensation around the lips or mouth area. This prodromal phase typically occurs 12-24 hours before visible blisters appear. Recognising these early symptoms is crucial as antiviral treatment is most effective when started promptly.

Treatment Options Available

Aciclovir represents the primary antiviral treatment for cold sores, available in both tablet and cream formulations. Aciclovir 400mg tablets may be prescribed for recurrent episodes, whilst aciclovir 5% cream can be applied topically. EverydayMeds stocks various antiviral treatments including aciclovir tablets and valaciclovir as alternative options. Treatment typically works best when initiated within the first 48 hours of symptom onset.

Managing Outbreaks

During active outbreaks, cold sores progress through distinct stages: initial tingling, blister formation, weeping phase, and finally crusting before healing. The complete cycle usually takes 7-10 days. Keeping the affected area clean and avoiding touching or picking at blisters helps prevent secondary bacterial infection and reduces transmission risk to others.

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