Compare Orlistat Strengths and Choose Your Treatment
Xenical vs Alli: Dose and Effectiveness Comparison
The key difference between Xenical and Alli lies in their orlistat content. Xenical contains 120mg orlistat per capsule (prescription-only), whilst Alli contains 60mg - exactly half the dose. Both work by blocking approximately one third of dietary fat absorption in the gut, but Xenical's higher dose may provide more comprehensive fat blocking support. Clinical studies suggest that 120mg orlistat can support more significant weight management when used alongside a reduced-calorie, lower-fat diet compared to the 60mg strength.
Generic Orlistat 120mg: Best Value Option
Generic orlistat 120mg provides identical clinical effects to branded Xenical at substantially lower cost. Both contain the same active ingredient at the same dose - the difference is purely the manufacturer. At EverydayMeds, generic orlistat 120mg costs £29.69 for 4 weeks with code EDM10, compared to £38.69 for branded Xenical. This represents significant monthly savings whilst maintaining the same prescription-strength fat blocking support for your weight management programme.
Prescription Assessment Required for 120mg Strength
Both Xenical and generic orlistat 120mg require prescription following clinical assessment by a UK-licensed prescriber. This ensures the treatment is appropriate for your individual health circumstances and BMI. Alli 60mg has different availability requirements but still needs careful consideration. Our online consultation process allows qualified prescribers to review your suitability without requiring a separate GP appointment. Treatment is prescribed where clinically appropriate for adults with suitable BMI levels.
How Each Strength Works in Practice
Orlistat works by inhibiting lipase enzymes in your digestive system, preventing approximately one third of dietary fat from being absorbed. The 120mg dose in Xenical and generic orlistat may block more dietary fat compared to Alli's 60mg dose, potentially supporting greater calorie reduction from fat intake. All strengths must be taken with each main meal containing fat - up to three times daily. The unabsorbed fat passes naturally through your body, which can cause gastrointestinal side effects, particularly with higher-fat meals.
Treatment Costs and Value Comparison
When comparing long-term costs, generic orlistat 120mg offers exceptional value. A 12-week supply costs £86.39 with EDM10, compared to £116.09 for branded Xenical - saving nearly £30. Alli 60mg costs £116.99 for 12 weeks with EDM10, making it similar in price to Xenical despite containing half the active ingredient dose. For most patients seeking prescription-strength weight loss support, generic orlistat 120mg provides the optimal combination of clinical effectiveness and affordability.
Side Effects: What to Expect
Both 120mg and 60mg orlistat can cause gastrointestinal side effects including oily stools, increased bowel movements, and oily spotting. These effects are more pronounced with higher doses and higher dietary fat intake. The 120mg strength may cause more frequent or noticeable side effects initially, but these typically reduce as you adapt to a lower-fat diet. Keeping meals to approximately 15g fat each significantly minimises side effects across all orlistat strengths.
Order Your Prescription Treatment Today
Ready to start your weight management journey? Complete our online clinical assessment to determine which orlistat strength is most suitable for you. Our UK-licensed prescribers will review your information and prescribe the most appropriate treatment. All medications are dispensed by our GPhC-registered Leicester pharmacy and delivered discreetly next day. Use code EDM10 for 10% off your order - available for both new and returning customers.
