How Orlistat 120mg Works for Weight Loss

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Understanding how orlistat works helps explain why it's prescribed for weight management. Orlistat blocks approximately one third of dietary fat absorption in your gut, preventing these calories from being absorbed into your body. The unabsorbed fat passes naturally through your digestive system. Generic orlistat 120mg starts from £32.99 (£29.69 with EDM10) for a 4-week supply. Following online clinical assessment by UK-licensed prescribers, orlistat is dispensed by our GPhC-registered Leicester pharmacy. Ready to start your weight management journey? Complete your consultation today.

  • Blocks approximately one third of dietary fat absorption in the gut
  • Works locally in digestive system - not absorbed into bloodstream
  • Available from £29.69 with EDM10 discount code
  • Next day delivery from GPhC-registered UK pharmacy
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pricing for mounjaro and wegovy weight loss

*Pricing shown in some areas of this page may not be up to date. Please refer to the “Our Pricing Table” or the price shown after your consultation for the latest live pricing.

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Why Orlistat's Mechanism Makes It Effective

How Orlistat 120mg Blocks Fat Absorption

Orlistat works by inhibiting lipase enzymes in your digestive system. These enzymes normally break down dietary fat so it can be absorbed into your body. When orlistat blocks these enzymes, approximately one third of the fat you eat cannot be digested or absorbed. This unabsorbed fat passes naturally through your body, reducing the calories absorbed from your meals.

Why This Mechanism Works for Weight Loss

By blocking approximately one third of dietary fat absorption, orlistat helps reduce your calorie intake from fat. Since fat contains 9 calories per gram (more than carbohydrates or protein), this reduction can support weight management when combined with a reduced-calorie, lower-fat diet. Generic orlistat 120mg provides this proven mechanism from £32.99 (£29.69 with EDM10) for 84 capsules.

Orlistat vs Xenical - Same Mechanism, Different Price

Both generic orlistat 120mg and branded Xenical 120mg contain the same active ingredient at the same dose. They work through the identical mechanism - blocking approximately one third of dietary fat absorption. The key difference is cost. Generic orlistat starts from £29.69 (4-week supply with EDM10), whilst Xenical costs £38.69 for the same period. Both require prescription following clinical assessment.

What to Expect When Orlistat Works

When orlistat blocks fat absorption, you may experience gastrointestinal effects including oily stools and increased bowel movements. These are signs the medication is working - the unabsorbed fat must exit your body. Keeping meals low in fat (approximately 15g per meal) helps minimise these effects whilst maintaining orlistat's weight management benefits.

Order Your Orlistat Treatment Today

Understanding how orlistat works demonstrates why it's prescribed for weight management. Complete your online clinical assessment to start treatment. Our UK-licensed prescribers will review your suitability, and if appropriate, your medication will be dispensed by our GPhC-registered pharmacy. Choose from 2, 4, 8, or 12-week supplies with 10% off every order using code EDM10.

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