The Science Behind How Orlistat Works
How Orlistat Blocks Fat Absorption
Orlistat works through a clinically-proven mechanism that inhibits lipase enzymes in your digestive system. These enzymes normally break down dietary fat for absorption. When orlistat blocks these enzymes, approximately one third of the fat you eat cannot be digested or absorbed into your body. This unabsorbed fat passes naturally through your digestive system, reducing the calories absorbed from fatty foods.
Why This Mechanism Makes Orlistat Effective
The fat-blocking action of orlistat provides measurable calorie reduction when combined with a lower-fat diet. Generic orlistat 120mg costs £29.69 for 4 weeks with EDM10, offering the same clinical effect as branded Xenical (£38.69 with EDM10). Alli 60mg provides half-strength fat blocking for those preferring a gentler approach. All three products work through identical lipase inhibition.
What to Expect When Orlistat Works
When orlistat works effectively, you may notice gastrointestinal effects that indicate fat is being blocked from absorption. These effects reduce significantly when you keep meals low in fat (approximately 15g per meal). Most patients find the mechanism works best alongside structured dietary changes, with effects becoming more manageable over time.
Orlistat vs Xenical vs Alli: Same Mechanism, Different Doses
All three products use the same fat-blocking mechanism. Orlistat 120mg and Xenical 120mg contain identical active ingredients - orlistat saves approximately £9 monthly compared to branded Xenical. Alli 60mg uses half the dose, blocking a smaller proportion of dietary fat. Our 8-week supply options (orlistat £57.59, Xenical £78.29, Alli £49.49 with EDM10) provide better value for continued treatment.
Order Orlistat Online Today
Now you understand how orlistat works to block approximately one third of dietary fat absorption, you can start your weight management journey. Our UK-licensed prescribers review your online assessment within 24 hours, with next day delivery available across the UK. Use code EDM10 for 10% off every order from our GPhC-registered Leicester pharmacy.
