Why Orlistat's Fat-Blocking Mechanism Works
How Orlistat Blocks Fat Absorption
Orlistat works through a scientifically proven mechanism that blocks approximately one third of the fat you eat from being absorbed. The medication inhibits lipase enzymes in your digestive system - these enzymes normally break down dietary fat so your body can absorb it. When these enzymes are blocked, roughly one third of consumed fat cannot be digested and passes naturally through your body instead of being stored as calories.
Why BMI Matters for Orlistat Eligibility
Orlistat may be suitable for adults with a BMI of 30 kg/m² or above, or those with a BMI of 28 kg/m² or above who have weight-related health conditions like type 2 diabetes or high blood pressure. Your BMI helps determine whether orlistat's fat-blocking mechanism will provide meaningful support for your weight management goals. Our UK-licensed prescribers assess your individual circumstances during the online clinical consultation.
Proven Fat-Blocking Technology You Can Trust
Unlike appetite suppressants that work on brain chemistry, orlistat acts locally in your gut without being significantly absorbed into your bloodstream. This targeted mechanism means the medication specifically addresses dietary fat absorption while allowing normal digestion of proteins and carbohydrates. Clinical studies demonstrate this approach can support meaningful weight loss when combined with a reduced-calorie, lower-fat diet.
Choose Your Orlistat Option
Generic orlistat 120mg offers the most cost-effective option at £32.99 for a 4-week supply (£29.69 with EDM10). Branded Xenical 120mg contains the identical active ingredient at £42.99 per month (£38.69 with EDM10). Both provide the same fat-blocking mechanism. Alli 60mg at £54.99 for 8 weeks offers a lower-strength alternative. All options require clinical assessment except where Alli is purchased without prescription.
Start Your Treatment Today
Now you understand how orlistat's fat-blocking mechanism works, you can access treatment through our streamlined online service. Complete the clinical questionnaire, receive prescriber review, and get genuine orlistat delivered discreetly to your door. Our GPhC-registered pharmacy ensures you receive authentic medication with full regulatory oversight. Use code EDM10 for 10% off your order - available for both new and returning customers.


