Understanding Orlistat's Mechanism - Why It Works
How Orlistat 120mg Works in Your Body
Orlistat works through a precise mechanism that targets fat absorption in your digestive system. As a lipase inhibitor, orlistat blocks the enzymes responsible for breaking down dietary fat. When you take orlistat 120mg with meals, it prevents approximately one third of the fat you eat from being digested and absorbed. This unabsorbed fat passes naturally through your body, reducing your overall calorie intake from dietary fat.
Why This Mechanism Makes Orlistat Effective
Unlike appetite suppressants that work in the brain, orlistat acts locally in your gut. This targeted approach means it directly addresses one of the main sources of excess calories - dietary fat. Each gram of fat contains 9 calories, so blocking approximately one third of fat absorption can significantly reduce calorie intake when combined with a lower-fat diet. Our orlistat 120mg costs £32.99 for 84 capsules (£29.69 with EDM10), providing 4 weeks of proven fat-blocking support.
Orlistat vs Xenical - Same Mechanism, Different Price
Both generic orlistat 120mg and branded Xenical 120mg work through identical mechanisms - blocking approximately one third of dietary fat absorption. The active ingredient and clinical effect are the same. Generic orlistat 120mg offers significant savings: 84 capsules cost £32.99 compared to £42.99 for Xenical. Many patients choose generic orlistat for the same fat-blocking mechanism at a lower price.
What Happens When You Take Orlistat
When you take one 120mg capsule with each main meal containing fat, orlistat immediately begins working in your digestive system. The medication inhibits pancreatic lipases - the enzymes that break down fat molecules. Without these enzymes functioning fully, approximately one third of dietary fat cannot be processed for absorption. This mechanism explains why orlistat is most effective when combined with a reduced-calorie, lower-fat diet.
Alli 60mg - Lower Dose, Same Mechanism
Alli contains 60mg orlistat - half the dose of prescription-strength orlistat. It works through the same fat-blocking mechanism but at a lower intensity. Alli 60mg (84 capsules) costs £54.99, while prescription orlistat 120mg (84 capsules) costs £32.99. Many patients find prescription-strength orlistat offers better value and stronger fat-blocking effects.
Order Orlistat Online - Clinical Assessment Included
Understanding how orlistat works helps you make an informed choice about weight management. Our online clinical assessment by UK-licensed prescribers determines if orlistat 120mg is suitable for your individual circumstances. Complete your health questionnaire today and access prescription orlistat from £16.89. Use code EDM10 for 10% off every order, with next day delivery from our GPhC-registered pharmacy.


