Best Treatment for Cold Sores and Fever Blisters

Cold sores and fever blisters are caused by the herpes simplex virus and can be effectively managed with the right treatment approach. Quick action at the first signs of symptoms can significantly reduce outbreak duration and severity. Antiviral medications like aciclovir are considered the gold standard treatment, available in both tablet and cream forms. EverydayMeds offers prescription aciclovir treatments to help manage cold sore outbreaks effectively.

  • Start treatment at first tingling sensation for best results
  • Aciclovir tablets (400mg) are most effective when taken early
  • Topical creams may help reduce symptoms if applied promptly
  • Most cold sores heal within 7-10 days with proper treatment
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Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Cold Sore.

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Aciclovir Tablets

From £12.99

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Aciclovir 5% Cream

From £8.99

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Valaciclovir

From £18.99

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Valtrex

From £34.99

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Aciclovir: The Most Effective Cold Sore Treatment

How Aciclovir Works Against Cold Sores

Aciclovir is an antiviral medication that targets the herpes simplex virus responsible for cold sores. By interfering with viral DNA replication, aciclovir can reduce the severity and duration of outbreaks when started early. Studies show that treatment initiated within 24 hours of symptom onset provides the greatest benefit.

Aciclovir Treatment Options

EverydayMeds offers several aciclovir formulations for cold sore treatment. Aciclovir 400mg tablets are typically prescribed for systemic treatment, particularly for frequent outbreaks or severe symptoms. The standard dosage is usually 400mg taken three times daily for five days, though your healthcare provider will determine the most appropriate regimen for your situation.

Aciclovir 5% cream provides localised treatment and can be applied directly to affected areas. This topical option may be preferred for mild outbreaks or when tablet treatment isn't suitable. The cream should be applied every four hours during waking hours, starting at the first sign of symptoms.

Alternative Antiviral Treatments

Valaciclovir represents another effective treatment option available through EverydayMeds. This medication converts to aciclovir in the body but offers improved bioavailability, meaning fewer doses may be required. Valaciclovir 500mg tablets are often prescribed as a convenient alternative, typically taken twice daily rather than three times.

When to Start Treatment

The timing of treatment initiation is crucial for optimal effectiveness. The prodromal stage - characterised by tingling, burning, or itching sensations - represents the ideal window for starting antiviral therapy. Once blisters have fully formed, antiviral medications may still provide some benefit but are generally less effective than early intervention.

Managing Recurrent Cold Sores

For individuals experiencing frequent cold sore outbreaks (six or more per year), suppressive therapy may be recommended. This approach involves taking daily antiviral medication to reduce outbreak frequency and severity. Your healthcare provider can assess whether suppressive treatment would be beneficial in your specific case.

How it
Works?

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Once you complete a short online assessment, you’ll be able to choose your preferred treatment and quantity from a list of safe, medically approved options tailored to you.

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