Complete Guide to Taking Aciclovir for Cold Sore Treatment
When to Start Taking Aciclovir
The most important factor in aciclovir effectiveness is timing. Begin treatment as soon as you notice the characteristic tingling, burning, or itching sensation that typically precedes visible cold sore development. Starting within 24 hours of symptom onset may help reduce the severity and duration of your outbreak. Cold sores on the side of the mouth often begin with subtle sensations that are easy to recognise if you've had previous episodes.
Standard Dosage Instructions
The typical prescription for cold sore treatment is aciclovir 400mg tablets taken five times daily for five consecutive days. This means taking one tablet approximately every four hours whilst awake - for example at 7am, 11am, 3pm, 7pm, and 11pm. EverydayMeds stocks aciclovir 400mg tablets suitable for this treatment regimen. Some healthcare providers may prescribe different strengths or frequencies based on individual circumstances.
How to Take the Tablets
Swallow aciclovir tablets whole with a full glass of water. You may take them with or without food, though taking with food might help if you experience stomach upset. Don't crush, chew, or break the tablets unless specifically instructed. Maintain regular intervals between doses to keep consistent levels of the medication in your system. Setting phone alarms can help ensure you don't miss doses during the treatment period.
Important Treatment Considerations
Complete the entire five-day course even if your cold sore begins improving earlier. Stopping treatment prematurely may allow the virus to continue replicating. Drink plenty of fluids whilst taking aciclovir to support kidney function. If you miss a dose, take it as soon as you remember, but don't double up if it's nearly time for the next scheduled dose.
Alternative Treatment Options
For those who experience frequent outbreaks, valaciclovir tablets offer an alternative with less frequent dosing requirements. EverydayMeds also provides topical aciclovir cream for localised application, though oral treatment is generally more effective for established cold sores. Your healthcare provider can advise whether suppressive therapy might be appropriate for recurrent episodes.






