Cold Sore Quick Reference Guide

Cold sores are small, painful blisters caused by the herpes simplex virus (HSV-1) that typically appear around the lips and mouth. Affecting up to 70% of the UK population, cold sores usually heal within 7-10 days but can be managed effectively with antiviral treatments. Early intervention with medications like aciclovir may help reduce outbreak duration and severity when treatment begins at the first sign of symptoms.

  • Cold sores progress through 5 distinct stages from tingling to complete healing
  • Antiviral treatments work best when started within 24-48 hours of first symptoms
  • Aciclovir tablets (400mg) are commonly prescribed for recurrent outbreaks
  • Topical aciclovir cream (5%) may provide relief for mild cases
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Available Treatments

Choose from a wide range of clinically-proven, safe, and effective treatments for Cold Sore.

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Aciclovir Tablets

From £12.99

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Aciclovir 5% Cream

From £8.99

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Valaciclovir

From £18.99

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Valtrex

From £34.99

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Treatment Options and Management

Recognising Cold Sore Stages

Understanding the stages of a cold sore outbreak can help determine the best time to begin treatment. The initial tingling stage typically lasts 1-2 days, followed by blister formation over days 2-4. The weeping stage (days 4-5) is when cold sores are most contagious, before crusting begins around day 5-8. Complete healing usually occurs within 7-10 days.

Antiviral Treatment Approaches

Aciclovir represents the most commonly prescribed antiviral for cold sore management. Available as 400mg tablets, aciclovir may help reduce outbreak severity when taken as soon as symptoms appear. The typical dosing involves taking tablets five times daily for five days, though individual treatment plans should always be discussed with a healthcare provider.

Topical vs Oral Treatments

EverydayMeds offers both oral aciclovir tablets and topical aciclovir 5% cream options. Oral treatments like aciclovir 400mg tablets are often preferred for recurrent outbreaks, whilst topical creams may be suitable for mild cases or those who cannot take oral medication. Alternative options include valaciclovir 500mg tablets, which may offer convenient twice-daily dosing.

When to Seek Treatment

Treatment effectiveness is typically highest when antiviral therapy begins within 24-48 hours of symptom onset. Those experiencing frequent outbreaks (more than 6 per year) may benefit from suppressive therapy, which requires medical consultation. EverydayMeds provides convenient access to prescription antiviral treatments following appropriate clinical assessment through our online consultation service.

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