Understanding Cold Sore Development and Treatment
Why Cold Sores Appear on the Side of the Mouth
Cold sores can appear anywhere around the lip area, including the corners and sides of the mouth. The herpes simplex virus lies dormant in nerve cells and may reactivate due to triggers such as stress, illness, sun exposure, or minor injuries to the face. When appearing at the mouth's corner, cold sores may be mistaken for angular cheilitis, but the characteristic blister formation helps distinguish HSV-1 infections.
Recognising the Five Stages
Stage 1 involves initial tingling or burning sensations lasting 1-2 days. Stage 2 sees small fluid-filled blisters forming over 2-4 days. Stage 3 is the weeping phase when blisters burst, typically days 4-5 and the most contagious period. Stage 4 involves crust formation from days 5-8. Stage 5 is complete healing, usually by day 10. Understanding these stages helps determine the most appropriate treatment timing.
Treatment Options Available
Prescription antiviral medications like aciclovir tablets may help reduce outbreak severity and duration when taken early. Aciclovir 400mg tablets work by inhibiting viral replication and are most effective when started within 72 hours of symptom onset. Topical treatments such as aciclovir 5% cream can also be applied directly to affected areas. For recurrent episodes, some patients may benefit from suppressive therapy with valaciclovir tablets.
When to Seek Treatment
Consider seeking treatment if you experience frequent outbreaks, severe symptoms, or if cold sores affect your quality of life. Online consultations through registered pharmacies like EverydayMeds can provide convenient access to prescription antiviral treatments. Early intervention may help minimise discomfort and reduce transmission risk to others, particularly important when cold sores appear in visible locations like the side of the mouth.






