Orlistat vs Xenical: Which Should You Choose?
Depression Risk: Orlistat vs Xenical Comparison
Both generic orlistat 120mg and branded Xenical 120mg contain exactly the same active ingredient at identical doses. Clinical studies don't list depression as a common side effect for either formulation. Anxiety is listed as an uncommon side effect (affecting up to 1 in 10 people), but depression isn't specifically documented in the prescribing information. Individual responses vary, and any persistent mood changes should be discussed with your prescriber.
Cost Comparison: Generic vs Branded
The primary difference between orlistat and Xenical is price. Generic orlistat 120mg costs £32.99 for a 4-week supply (£29.69 with EDM10), while branded Xenical costs £42.99 for the same quantity (£38.69 with EDM10). This represents savings of approximately £9 per month by choosing generic orlistat. Both work identically - blocking approximately one third of dietary fat absorption when used alongside a reduced-calorie, lower-fat diet.
Complete Price Breakdown
Generic orlistat 120mg: 2-week supply £16.89 (£15.20 with EDM10), 8-week supply £63.99 (£57.59 with EDM10), 12-week supply £95.99 (£86.39 with EDM10). Branded Xenical 120mg: 2-week supply £21.50 (£19.35 with EDM10), 8-week supply £86.99 (£78.29 with EDM10), 12-week supply £128.99 (£116.09 with EDM10). Use code EDM10 for 10% off every order.
Alternative Option: Alli 60mg
Alli 60mg offers half the dose of prescription-strength orlistat. At £28.99 for a 4-week supply (£26.09 with EDM10), it provides a lower-strength starting option. While less potent than 120mg formulations, Alli typically produces milder gastrointestinal side effects due to the reduced dose.
How to Order
Both orlistat 120mg and Xenical 120mg require clinical assessment by a UK-licensed prescriber. Complete our online health questionnaire, including medical history and BMI information. Following prescriber review and approval, your chosen treatment is dispensed by our GPhC-registered pharmacy in Leicester and delivered discreetly with next-day delivery across the UK. The prescription is included in the price - no separate GP appointment needed.
