Which Should You Buy: Orlistat or Xenical?
Orlistat vs Xenical: The Key Differences
When comparing orlistat 120mg and Xenical 120mg, the most important fact is they contain exactly the same active ingredient at the same dose. Both work by inhibiting lipase enzymes in the gut, blocking approximately one third of dietary fat from being absorbed. The unabsorbed fat passes naturally through your digestive system. Clinically, there is no difference in effectiveness between generic orlistat and branded Xenical.
The primary difference is cost. Generic orlistat 120mg starts from £29.69 for a 4-week supply (84 capsules) with code EDM10, while Xenical costs £38.69 for the same quantity. Over a 12-week treatment period, choosing generic orlistat saves you £29.70 compared to Xenical branded capsules.
Orlistat 120mg Pricing
Our generic orlistat 120mg offers exceptional value without compromising on quality. A 2-week supply (42 capsules) costs £15.20 with EDM10, perfect for trying the treatment. The 4-week supply at £29.69 provides one month's treatment, while our 8-week option (168 capsules) costs £57.59. For longer treatment periods, the 12-week supply (252 capsules) offers the best value at £86.39 with discount code EDM10.
Xenical 120mg Branded Option
Some patients prefer branded Xenical 120mg, manufactured by Roche. While clinically identical to generic orlistat, Xenical provides the reassurance of an established brand name. Xenical pricing starts at £19.35 for 2 weeks, £38.69 for 4 weeks, £78.29 for 8 weeks, and £116.09 for 12 weeks (all with EDM10 discount applied).
Alli 60mg: Lower-Strength Alternative
For those preferring a gentler approach, Alli 60mg contains half the dose of prescription-strength orlistat. While less potent than the 120mg options, Alli may cause fewer gastrointestinal side effects. Alli pricing includes 4-week supply for £26.09, 8-week for £49.49, and 12-week for £116.99 with code EDM10.
How to Order Online
Both orlistat 120mg and Xenical 120mg require a prescription following clinical assessment. Complete our online health questionnaire, which is reviewed by UK-licensed prescribers. If treatment is deemed appropriate for your circumstances, your prescription is dispensed by our GPhC-registered pharmacy and dispatched with next-day delivery. The prescription consultation is included in the price - no separate GP appointment required.
Which Option to Choose
Choose generic orlistat 120mg if you want the most cost-effective option without compromising clinical effectiveness. Select Xenical 120mg if you prefer the branded version. Consider Alli 60mg if you want to start with a lower dose. All options work by blocking approximately one third of dietary fat absorption and must be used alongside a reduced-calorie, lower-fat diet and regular physical activity. Your prescriber will help determine the most suitable option during your clinical assessment.


