When to Start Your Cold Sore Treatment
Recognising the Early Signs
The most effective time to begin cold sore treatment is during the prodromal phase - the initial tingling, burning, or itching sensation that typically occurs 12-24 hours before blisters appear. At this early stage, antiviral medications like aciclovir can significantly reduce the severity and duration of the outbreak.
Optimal Timing for Aciclovir Tablets
Aciclovir 400mg tablets, available through EverydayMeds, should ideally be started within 24-48 hours of the first symptoms. The typical dosing schedule involves taking tablets every 4-6 hours (usually 5 times daily) for 5-7 days. Taking aciclovir with or after food may help reduce potential stomach upset, though it can be taken on an empty stomach if necessary.
Topical Treatment Timing
Aciclovir 5% cream should be applied at the first sign of symptoms and continued every 4 hours (5 times daily) for 4 days minimum. The cream works best when applied before blisters fully develop. Clean hands thoroughly before and after application to prevent spreading the infection.
Late Treatment Considerations
Whilst early treatment provides the best outcomes, starting antiviral therapy even after blisters have formed may still help reduce healing time and discomfort. If you've missed the early window, don't delay - begin treatment as soon as possible. EverydayMeds also stocks alternative treatments like valaciclovir, which may be prescribed if standard aciclovir isn't suitable.
Treatment Course Completion
Complete the full prescribed course even if symptoms improve quickly. Stopping treatment early may allow the virus to become active again, potentially prolonging the outbreak or increasing the risk of recurrence.






